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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A6OS
All Species:
25.45
Human Site:
Y198
Identified Species:
46.67
UniProt:
Q96CW6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CW6
NP_115554.1
309
35086
Y198
Q
K
H
D
D
Y
V
Y
D
I
Y
Y
L
E
T
Chimpanzee
Pan troglodytes
XP_511054
165
19324
I56
H
D
D
Y
V
Y
D
I
Y
Y
L
E
T
A
T
Rhesus Macaque
Macaca mulatta
XP_001091334
216
24947
I107
H
D
D
Y
V
Y
D
I
Y
Y
L
E
T
A
T
Dog
Lupus familis
XP_853763
311
35399
Y200
E
Q
K
D
D
Y
V
Y
D
I
Y
Y
L
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q7TPE5
306
35022
Y196
K
H
N
D
D
Y
V
Y
D
I
Y
Y
M
E
M
Rat
Rattus norvegicus
NP_647544
305
35013
Y195
K
H
S
D
D
Y
V
Y
D
I
Y
Y
M
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505580
355
39940
Y238
D
E
E
E
D
F
E
Y
D
I
Y
Y
R
K
T
Chicken
Gallus gallus
XP_413987
328
36922
Y218
R
E
K
D
E
Y
V
Y
D
I
Y
C
M
E
T
Frog
Xenopus laevis
A2BDB7
313
36408
D203
S
E
H
R
E
Y
V
D
E
Y
V
Y
D
I
Y
Zebra Danio
Brachydanio rerio
Q5U3I2
326
37021
Y212
E
K
E
D
D
Y
V
Y
D
L
Y
Y
Q
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496943
251
27938
E142
P
E
V
V
G
N
L
E
Q
D
I
E
G
A
D
Sea Urchin
Strong. purpuratus
XP_001191447
325
35365
K213
D
I
T
C
N
S
V
K
M
I
R
E
K
L
V
Poplar Tree
Populus trichocarpa
XP_002325660
352
40266
Y230
L
D
V
D
D
Y
V
Y
D
Y
Y
T
V
K
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.1
57.2
80.3
N.A.
76.3
76.6
N.A.
41.1
47.5
44.4
43.8
N.A.
N.A.
N.A.
22.6
21.8
Protein Similarity:
100
53.4
62.4
87.1
N.A.
83.5
84.1
N.A.
57.1
64.6
59.7
60.1
N.A.
N.A.
N.A.
40.4
38.1
P-Site Identity:
100
13.3
13.3
73.3
N.A.
66.6
66.6
N.A.
46.6
60
26.6
73.3
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
13.3
13.3
86.6
N.A.
86.6
80
N.A.
73.3
86.6
46.6
86.6
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
60
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
16
24
16
54
54
0
16
8
62
8
0
0
8
0
16
% D
% Glu:
16
31
16
8
16
0
8
8
8
0
0
31
0
47
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% G
% His:
16
16
16
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
16
0
54
8
0
0
8
0
% I
% Lys:
16
16
16
0
0
0
0
8
0
0
0
0
8
16
0
% K
% Leu:
8
0
0
0
0
0
8
0
0
8
16
0
16
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
24
0
24
% M
% Asn:
0
0
8
0
8
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
8
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
0
8
16
0
47
% T
% Val:
0
0
16
8
16
0
70
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
16
0
77
0
62
16
31
62
54
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _