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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC58 All Species: 18.18
Human Site: S19 Identified Species: 28.57
UniProt: Q96CX6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CX6 NP_001093148.1 371 40586 S19 G E A E L N W S R L S V S T E
Chimpanzee Pan troglodytes XP_516671 529 57685 S177 G E A E L N W S R L S V S T E
Rhesus Macaque Macaca mulatta XP_001104236 488 53100 S136 G E A E L N W S R L S V S T E
Dog Lupus familis XP_545123 366 39974 S19 N L S R L T L S P E T L E S E
Cat Felis silvestris
Mouse Mus musculus Q3UGP9 366 40121 S19 N W S R L S V S A E A L E S E
Rat Rattus norvegicus XP_001069929 366 40109 S19 N W S R L S V S A E A L E S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510174 324 35879
Chicken Gallus gallus Q5ZLN0 603 67457 W56 G E V P Q H V W R I N L D T P
Frog Xenopus laevis Q32NT4 350 39401 L18 N V L N L T H L G L E N L N L
Zebra Danio Brachydanio rerio Q6DHL5 238 26500
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727428 377 41315 G22 E Q K T L D F G R M S L D L V
Honey Bee Apis mellifera XP_394765 365 41792 F18 Q W Y G E F L F M E N Y T S D
Nematode Worm Caenorhab. elegans NP_001022864 375 42232 L24 T R R T D A N L Y P N G S T K
Sea Urchin Strong. purpuratus XP_797077 298 33688
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SSD1 496 54487 S23 I V S P L V R S F T V I T S D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.9 75.8 93.8 N.A. 93.5 93.8 N.A. 58.7 22.2 67.1 23.1 N.A. 43.2 43.6 45.8 45
Protein Similarity: 100 70.1 76 96.2 N.A. 95.9 95.9 N.A. 67.9 36.3 76.8 39.8 N.A. 58.3 58.7 60.2 58.2
P-Site Identity: 100 100 100 20 N.A. 20 20 N.A. 0 26.6 13.3 0 N.A. 20 0 13.3 0
P-Site Similarity: 100 100 100 46.6 N.A. 53.3 53.3 N.A. 0 53.3 13.3 0 N.A. 53.3 26.6 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 7 0 0 14 0 14 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 7 0 0 0 0 0 0 14 0 14 % D
% Glu: 7 27 0 20 7 0 0 0 0 27 7 0 20 0 40 % E
% Phe: 0 0 0 0 0 7 7 7 7 0 0 0 0 0 0 % F
% Gly: 27 0 0 7 0 0 0 7 7 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 0 0 0 7 0 7 0 0 0 % I
% Lys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 0 7 7 0 60 0 14 14 0 27 0 34 7 7 7 % L
% Met: 0 0 0 0 0 0 0 0 7 7 0 0 0 0 0 % M
% Asn: 27 0 0 7 0 20 7 0 0 0 20 7 0 7 0 % N
% Pro: 0 0 0 14 0 0 0 0 7 7 0 0 0 0 7 % P
% Gln: 7 7 0 0 7 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 7 7 20 0 0 7 0 34 0 0 0 0 0 0 % R
% Ser: 0 0 27 0 0 14 0 47 0 0 27 0 27 34 0 % S
% Thr: 7 0 0 14 0 14 0 0 0 7 7 0 14 34 0 % T
% Val: 0 14 7 0 0 7 20 0 0 0 7 20 0 0 7 % V
% Trp: 0 20 0 0 0 0 20 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 7 0 0 0 0 0 7 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _