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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRRC58 All Species: 22.73
Human Site: S58 Identified Species: 35.71
UniProt: Q96CX6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96CX6 NP_001093148.1 371 40586 S58 L P H N R L V S L P R A L G S
Chimpanzee Pan troglodytes XP_516671 529 57685 S216 L P H N R L V S L P R A L G S
Rhesus Macaque Macaca mulatta XP_001104236 488 53100 S175 L P H N R L V S L P R A L G S
Dog Lupus familis XP_545123 366 39974 S53 L P H S R L A S L P R A L G S
Cat Felis silvestris
Mouse Mus musculus Q3UGP9 366 40121 S53 L P Y N R L T S L P R A L G G
Rat Rattus norvegicus XP_001069929 366 40109 S53 L P Y N R L T S L P R A L G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510174 324 35879 S21 E A L R V S V S P S G T V G M
Chicken Gallus gallus Q5ZLN0 603 67457 V135 E N L Q K L D V S H N K L K S
Frog Xenopus laevis Q32NT4 350 39401 R45 Q I L L P H N R L V V L P P L
Zebra Danio Brachydanio rerio Q6DHL5 238 26500
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_727428 377 41315 G70 P R L L L Q F G N L K I L D L
Honey Bee Apis mellifera XP_394765 365 41792 D44 D L S Y L M L D T Q L L N D H
Nematode Worm Caenorhab. elegans NP_001022864 375 42232 D67 P Q N V K K L D L T H N S F V
Sea Urchin Strong. purpuratus XP_797077 298 33688
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SSD1 496 54487 P174 R E N G F L G P I P D E L G N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69.9 75.8 93.8 N.A. 93.5 93.8 N.A. 58.7 22.2 67.1 23.1 N.A. 43.2 43.6 45.8 45
Protein Similarity: 100 70.1 76 96.2 N.A. 95.9 95.9 N.A. 67.9 36.3 76.8 39.8 N.A. 58.3 58.7 60.2 58.2
P-Site Identity: 100 100 100 86.6 N.A. 80 86.6 N.A. 20 20 6.6 0 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. 26.6 26.6 6.6 0 N.A. 13.3 13.3 26.6 0
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 7 0 0 0 0 40 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 7 14 0 0 7 0 0 14 0 % D
% Glu: 14 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 7 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 7 0 0 7 7 0 0 7 0 0 54 7 % G
% His: 0 0 27 0 0 7 0 0 0 7 7 0 0 0 7 % H
% Ile: 0 7 0 0 0 0 0 0 7 0 0 7 0 0 0 % I
% Lys: 0 0 0 0 14 7 0 0 0 0 7 7 0 7 0 % K
% Leu: 40 7 27 14 14 54 14 0 54 7 7 14 60 0 14 % L
% Met: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 7 % M
% Asn: 0 7 14 34 0 0 7 0 7 0 7 7 7 0 7 % N
% Pro: 14 40 0 0 7 0 0 7 7 47 0 0 7 7 0 % P
% Gln: 7 7 0 7 0 7 0 0 0 7 0 0 0 0 0 % Q
% Arg: 7 7 0 7 40 0 0 7 0 0 40 0 0 0 0 % R
% Ser: 0 0 7 7 0 7 0 47 7 7 0 0 7 0 40 % S
% Thr: 0 0 0 0 0 0 14 0 7 7 0 7 0 0 0 % T
% Val: 0 0 0 7 7 0 27 7 0 7 7 0 7 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 14 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _