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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC58
All Species:
24.55
Human Site:
Y280
Identified Species:
38.57
UniProt:
Q96CX6
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96CX6
NP_001093148.1
371
40586
Y280
R
N
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Chimpanzee
Pan troglodytes
XP_516671
529
57685
Y438
R
N
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Rhesus Macaque
Macaca mulatta
XP_001104236
488
53100
Y397
R
N
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Dog
Lupus familis
XP_545123
366
39974
Y275
R
N
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UGP9
366
40121
Y275
R
S
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Rat
Rattus norvegicus
XP_001069929
366
40109
Y275
R
S
I
S
Y
T
P
Y
D
L
P
G
N
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510174
324
35879
V240
R
D
L
P
E
N
L
V
R
Y
L
D
L
A
S
Chicken
Gallus gallus
Q5ZLN0
603
67457
E380
D
K
A
S
P
N
E
E
P
P
V
T
A
M
T
Frog
Xenopus laevis
Q32NT4
350
39401
W264
H
G
I
P
Y
C
P
W
E
L
P
E
N
L
L
Zebra Danio
Brachydanio rerio
Q6DHL5
238
26500
A154
A
E
V
A
E
L
Q
A
I
E
I
N
L
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727428
377
41315
Y292
S
G
Q
R
P
G
P
Y
D
I
P
R
T
L
A
Honey Bee
Apis mellifera
XP_394765
365
41792
H266
R
F
V
S
D
M
T
H
N
P
P
S
L
L
E
Nematode Worm
Caenorhab. elegans
NP_001022864
375
42232
L289
N
Y
H
K
V
P
N
L
D
E
I
L
P
S
D
Sea Urchin
Strong. purpuratus
XP_797077
298
33688
M213
E
D
L
P
G
E
V
M
L
Y
L
D
S
A
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SSD1
496
54487
R395
T
G
P
V
P
F
E
R
D
T
V
W
R
M
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.9
75.8
93.8
N.A.
93.5
93.8
N.A.
58.7
22.2
67.1
23.1
N.A.
43.2
43.6
45.8
45
Protein Similarity:
100
70.1
76
96.2
N.A.
95.9
95.9
N.A.
67.9
36.3
76.8
39.8
N.A.
58.3
58.7
60.2
58.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
6.6
6.6
53.3
0
N.A.
33.3
26.6
6.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
66.6
13.3
N.A.
40
46.6
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
7
0
0
0
7
0
0
0
0
7
14
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
0
0
7
0
0
0
60
0
0
14
0
0
7
% D
% Glu:
7
7
0
0
14
7
14
7
7
14
0
7
0
0
7
% E
% Phe:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
20
0
0
7
7
0
0
0
0
0
40
0
0
0
% G
% His:
7
0
7
0
0
0
0
7
0
0
0
0
0
0
0
% H
% Ile:
0
0
47
0
0
0
0
0
7
7
14
0
0
0
0
% I
% Lys:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
14
0
0
7
7
7
7
47
14
7
20
60
47
% L
% Met:
0
0
0
0
0
7
0
7
0
0
0
0
0
14
0
% M
% Asn:
7
27
0
0
0
14
7
0
7
0
0
7
47
7
0
% N
% Pro:
0
0
7
20
20
7
54
0
7
14
60
0
7
0
0
% P
% Gln:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% Q
% Arg:
54
0
0
7
0
0
0
7
7
0
0
7
7
0
14
% R
% Ser:
7
14
0
54
0
0
0
0
0
0
0
7
7
7
7
% S
% Thr:
7
0
0
0
0
40
7
0
0
7
0
7
7
0
7
% T
% Val:
0
0
14
7
7
0
7
7
0
0
14
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% W
% Tyr:
0
7
0
0
47
0
0
47
0
14
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _