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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASD2
All Species:
31.82
Human Site:
Y246
Identified Species:
50
UniProt:
Q96D21
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D21
NP_055125.2
266
30366
Y246
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Chimpanzee
Pan troglodytes
XP_525580
278
31597
Y258
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Rhesus Macaque
Macaca mulatta
XP_001113531
258
28804
Y238
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Dog
Lupus familis
XP_538405
561
61514
Y541
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Cat
Felis silvestris
Mouse
Mus musculus
O35626
280
31665
Y260
S
V
H
S
D
L
M
Y
I
R
E
K
T
S
V
Rat
Rattus norvegicus
P63033
266
30178
Y246
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513067
266
30311
Y246
S
V
N
S
D
L
K
Y
I
K
A
K
V
L
R
Chicken
Gallus gallus
XP_416293
265
30557
Y245
S
V
N
S
D
L
K
Y
I
K
S
K
V
L
R
Frog
Xenopus laevis
Q7ZXH7
184
20815
R167
D
L
V
R
Q
I
N
R
K
T
P
V
P
G
K
Zebra Danio
Brachydanio rerio
Q6TEN1
184
20809
R167
D
L
V
R
Q
I
N
R
K
T
P
V
T
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08645
184
20845
S168
V
R
Q
I
N
K
K
S
P
E
K
K
Q
K
K
Honey Bee
Apis mellifera
XP_393455
354
39154
I320
S
I
R
T
D
L
M
I
M
R
T
K
T
C
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780235
286
32177
Q250
S
L
R
S
D
L
L
Q
V
R
N
N
A
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P13856
272
30372
G252
S
G
S
S
N
R
T
G
I
S
A
T
S
Q
Q
Red Bread Mold
Neurospora crassa
P22126
213
24008
V197
G
A
V
K
Q
M
D
V
G
D
E
D
V
Q
A
Conservation
Percent
Protein Identity:
100
95.6
70.3
46.3
N.A.
61.4
95.1
N.A.
93.2
89.8
28.5
27.8
N.A.
27.8
40.4
N.A.
47.5
Protein Similarity:
100
95.6
75.9
46.8
N.A.
77.1
96.6
N.A.
96.6
95.1
47.3
46.2
N.A.
45.8
55.3
N.A.
65.7
P-Site Identity:
100
100
100
100
N.A.
53.3
100
N.A.
100
93.3
0
0
N.A.
13.3
26.6
N.A.
40
P-Site Similarity:
100
100
100
100
N.A.
66.6
100
N.A.
100
100
20
20
N.A.
33.3
53.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29
30.8
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
49.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
47
0
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% C
% Asp:
14
0
0
0
67
0
7
0
0
7
0
7
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
7
14
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
7
7
0
0
0
0
14
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
0
7
0
14
0
7
60
0
0
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
54
0
14
47
7
67
0
7
20
% K
% Leu:
0
20
0
0
0
67
7
0
0
0
0
0
0
54
0
% L
% Met:
0
0
0
0
0
7
14
0
7
0
0
0
0
0
0
% M
% Asn:
0
0
47
0
14
0
14
0
0
0
7
7
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
14
0
7
0
0
% P
% Gln:
0
0
7
0
20
0
0
7
0
0
0
0
7
14
7
% Q
% Arg:
0
7
14
14
0
7
0
14
0
20
0
0
0
0
54
% R
% Ser:
74
0
7
67
0
0
0
7
0
7
7
0
7
7
7
% S
% Thr:
0
0
0
7
0
0
7
0
0
14
7
7
20
0
0
% T
% Val:
7
54
20
0
0
0
0
7
7
0
0
14
54
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _