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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORAI1
All Species:
5.45
Human Site:
S27
Identified Species:
12
UniProt:
Q96D31
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D31
NP_116179.2
301
32668
S27
G
G
S
T
T
S
G
S
R
R
S
R
R
R
S
Chimpanzee
Pan troglodytes
XP_528664
301
32521
S27
G
G
S
T
T
S
G
S
R
R
S
R
R
R
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543386
361
38890
G84
G
G
G
S
T
T
S
G
S
R
R
S
R
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BWG9
304
33043
R29
S
S
T
S
G
S
R
R
S
R
R
R
S
G
D
Rat
Rattus norvegicus
Q5M848
304
33021
R28
G
S
S
T
S
G
S
R
R
S
R
R
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510413
507
55202
P104
K
A
V
R
G
N
T
P
G
R
K
G
P
P
A
Chicken
Gallus gallus
Q5ZL05
226
25112
Frog
Xenopus laevis
Q5EAU0
258
28719
L18
S
R
P
C
S
K
Q
L
Q
E
E
V
S
Y
P
Zebra Danio
Brachydanio rerio
Q6TLE6
222
24614
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U6B8
351
38488
T99
N
S
A
G
F
Q
R
T
S
I
S
N
S
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09232
293
32006
G42
V
A
N
W
K
N
S
G
G
A
G
D
P
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
N.A.
78.6
N.A.
89.4
89.1
N.A.
45.7
69
70.7
63.7
N.A.
38.7
N.A.
34.5
N.A.
Protein Similarity:
100
99.3
N.A.
80.8
N.A.
92.4
92.4
N.A.
51
71
76.4
69
N.A.
49.5
N.A.
52.4
N.A.
P-Site Identity:
100
100
N.A.
40
N.A.
20
40
N.A.
6.6
0
0
0
N.A.
6.6
N.A.
0
N.A.
P-Site Similarity:
100
100
N.A.
53.3
N.A.
33.3
46.6
N.A.
20
0
13.3
0
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
0
0
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
37
28
10
10
19
10
19
19
19
0
10
10
0
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
10
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
19
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
10
0
0
0
0
10
0
0
0
0
19
10
10
% P
% Gln:
0
0
0
0
0
10
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
10
0
0
19
19
28
46
28
37
37
28
10
% R
% Ser:
19
28
28
19
19
28
28
19
28
10
28
10
28
10
19
% S
% Thr:
0
0
10
28
28
10
10
10
0
0
0
0
0
0
10
% T
% Val:
10
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _