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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NMD3
All Species:
33.94
Human Site:
S490
Identified Species:
57.44
UniProt:
Q96D46
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D46
NP_057022.2
503
57603
S490
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Chimpanzee
Pan troglodytes
XP_516854
503
57603
S490
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Rhesus Macaque
Macaca mulatta
XP_001096557
503
57599
S490
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Dog
Lupus familis
XP_545261
670
75965
S656
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99L48
503
57593
S490
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Rat
Rattus norvegicus
NP_001101152
503
57702
S490
M
L
E
D
L
R
I
S
Q
D
A
T
G
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422813
504
57548
S490
M
L
E
D
L
H
I
S
E
D
A
T
G
G
E
Frog
Xenopus laevis
Q6GNS3
504
58079
S490
M
L
E
D
L
H
I
S
Q
D
A
T
G
E
E
Zebra Danio
Brachydanio rerio
Q5BLF0
505
57713
S492
M
L
E
D
L
S
L
S
D
A
T
G
G
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477332
521
59106
E502
M
L
E
D
M
T
L
E
C
A
D
D
E
M
G
Honey Bee
Apis mellifera
XP_624393
503
58150
D491
T
L
E
E
M
L
D
D
L
A
I
N
D
V
E
Nematode Worm
Caenorhab. elegans
NP_492114
513
58599
D495
M
L
D
D
L
K
F
D
D
E
E
M
K
E
A
Sea Urchin
Strong. purpuratus
XP_788633
513
58209
G496
M
L
E
D
F
H
I
G
G
N
E
G
A
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38861
518
59096
M503
L
L
D
E
L
D
E
M
T
L
E
D
G
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97
72
N.A.
94.8
94.8
N.A.
N.A.
80.9
81.7
76.8
N.A.
51.4
54
49.3
60.8
Protein Similarity:
100
99.8
98
74.1
N.A.
98.6
98.2
N.A.
N.A.
91
91.4
89.3
N.A.
69
73.7
69.1
76.4
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
86.6
100
53.3
N.A.
26.6
20
33.3
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
93.3
100
60
N.A.
40
33.3
46.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
43.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
66.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
22
58
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
15
86
0
8
8
15
15
58
8
15
8
8
0
% D
% Glu:
0
0
86
15
0
0
8
8
8
8
22
0
8
65
79
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
0
15
72
8
15
% G
% His:
0
0
0
0
0
58
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
65
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% K
% Leu:
8
100
0
0
79
8
15
0
8
8
0
0
0
0
0
% L
% Met:
86
0
0
0
15
0
0
8
0
0
0
8
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
65
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
8
0
0
8
0
8
58
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _