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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK4
All Species:
5.45
Human Site:
S122
Identified Species:
9.23
UniProt:
Q96D53
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D53
NP_001136027.1
544
60069
S122
M
P
G
G
R
L
Q
S
E
G
G
S
G
L
D
Chimpanzee
Pan troglodytes
XP_512672
501
55211
Q101
A
N
A
E
R
I
V
Q
T
L
C
T
V
R
G
Rhesus Macaque
Macaca mulatta
XP_001097315
544
59987
S122
L
P
G
G
H
L
Q
S
E
G
G
S
G
P
D
Dog
Lupus familis
XP_541612
484
54091
K113
V
L
T
E
V
A
K
K
S
L
P
G
G
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q566J8
533
59213
H123
L
P
G
G
S
L
Q
H
E
G
V
S
G
L
G
Rat
Rattus norvegicus
Q6AY19
528
58886
G118
V
T
K
K
S
L
P
G
G
S
L
Q
H
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517948
515
57559
P101
G
L
S
G
R
Q
P
P
A
A
G
S
L
L
S
Chicken
Gallus gallus
XP_415040
648
72471
S241
S
L
R
P
E
E
R
S
G
K
K
A
V
M
D
Frog
Xenopus laevis
NP_001087459
560
63668
D149
L
N
R
E
E
K
Q
D
N
N
H
S
I
L
E
Zebra Danio
Brachydanio rerio
Q5RGU1
602
66969
G212
L
R
S
E
D
K
N
G
N
K
K
A
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624948
466
53616
A96
L
C
K
V
R
G
A
A
L
K
I
G
Q
I
L
Nematode Worm
Caenorhab. elegans
Q18486
755
83597
R342
R
T
F
G
I
G
K
R
L
Q
E
E
G
I
P
Sea Urchin
Strong. purpuratus
XP_791783
633
70501
E231
V
R
R
G
L
G
L
E
E
T
G
G
K
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27697
501
56723
A101
A
K
G
I
S
E
V
A
K
G
N
S
P
T
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
96.5
81.4
N.A.
85.2
82.7
N.A.
70.7
50.6
58.3
50.6
N.A.
N.A.
44.6
34.5
46.9
Protein Similarity:
100
84
97.4
84.9
N.A.
89.7
88.5
N.A.
78.4
63.4
70.7
63.9
N.A.
N.A.
62.3
47.8
60.5
P-Site Identity:
100
6.6
80
6.6
N.A.
66.6
6.6
N.A.
33.3
13.3
20
13.3
N.A.
N.A.
6.6
13.3
33.3
P-Site Similarity:
100
20
86.6
20
N.A.
73.3
13.3
N.A.
33.3
33.3
33.3
26.6
N.A.
N.A.
26.6
26.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
0
0
8
8
15
8
8
0
15
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
36
% D
% Glu:
0
0
0
29
15
15
0
8
29
0
8
8
0
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
29
43
0
22
0
15
15
29
29
22
36
0
22
% G
% His:
0
0
0
0
8
0
0
8
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
8
8
8
0
0
0
0
8
0
8
15
0
% I
% Lys:
0
8
15
8
0
15
15
8
8
22
15
0
8
0
0
% K
% Leu:
36
22
0
0
8
29
8
0
15
15
8
0
8
43
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
15
0
0
0
0
8
0
15
8
8
0
0
0
0
% N
% Pro:
0
22
0
8
0
0
15
8
0
0
8
0
8
8
8
% P
% Gln:
0
0
0
0
0
8
29
8
0
8
0
8
8
0
0
% Q
% Arg:
8
15
22
0
29
0
8
8
0
0
0
0
0
15
0
% R
% Ser:
8
0
15
0
22
0
0
22
8
8
0
43
0
0
8
% S
% Thr:
0
15
8
0
0
0
0
0
8
8
0
8
0
8
0
% T
% Val:
22
0
0
8
8
0
15
0
0
0
8
0
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _