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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK4
All Species:
46.06
Human Site:
S420
Identified Species:
77.95
UniProt:
Q96D53
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D53
NP_001136027.1
544
60069
S420
R
D
C
V
L
Q
K
S
R
D
L
K
F
L
T
Chimpanzee
Pan troglodytes
XP_512672
501
55211
S377
R
D
C
V
L
Q
K
S
R
D
L
K
F
L
T
Rhesus Macaque
Macaca mulatta
XP_001097315
544
59987
S420
R
D
R
V
L
Q
K
S
R
D
L
K
F
L
T
Dog
Lupus familis
XP_541612
484
54091
S379
R
D
R
V
L
K
K
S
R
D
L
K
F
L
T
Cat
Felis silvestris
Mouse
Mus musculus
Q566J8
533
59213
S421
R
D
R
V
L
Q
K
S
Q
D
L
K
F
L
T
Rat
Rattus norvegicus
Q6AY19
528
58886
S416
R
D
R
V
L
Q
K
S
Q
D
L
K
F
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517948
515
57559
S399
R
E
R
V
L
Q
K
S
Q
D
L
K
F
L
T
Chicken
Gallus gallus
XP_415040
648
72471
S539
R
E
R
V
L
K
K
S
I
E
M
K
F
L
T
Frog
Xenopus laevis
NP_001087459
560
63668
S447
R
A
K
V
L
Q
K
S
Q
D
L
R
F
L
T
Zebra Danio
Brachydanio rerio
Q5RGU1
602
66969
S493
R
E
G
V
L
K
Q
S
I
D
M
K
F
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624948
466
53616
S363
R
K
K
I
L
N
L
S
R
D
M
G
F
L
T
Nematode Worm
Caenorhab. elegans
Q18486
755
83597
S644
K
K
K
I
I
E
Y
S
R
E
I
G
F
L
T
Sea Urchin
Strong. purpuratus
XP_791783
633
70501
L529
R
E
E
V
L
V
N
L
Q
K
L
Q
F
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27697
501
56723
S399
R
K
G
A
Y
E
M
S
V
Q
L
G
Y
L
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
96.5
81.4
N.A.
85.2
82.7
N.A.
70.7
50.6
58.3
50.6
N.A.
N.A.
44.6
34.5
46.9
Protein Similarity:
100
84
97.4
84.9
N.A.
89.7
88.5
N.A.
78.4
63.4
70.7
63.9
N.A.
N.A.
62.3
47.8
60.5
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
86.6
N.A.
80
60
73.3
60
N.A.
N.A.
53.3
33.3
46.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
86.6
86.6
N.A.
N.A.
66.6
73.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
43
0
0
0
0
0
0
0
72
0
0
0
0
0
% D
% Glu:
0
29
8
0
0
15
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
93
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
22
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
15
8
0
0
0
15
0
8
0
0
0
0
% I
% Lys:
8
22
22
0
0
22
65
0
0
8
0
65
0
0
0
% K
% Leu:
0
0
0
0
86
0
8
8
0
0
72
0
0
100
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
22
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
50
8
0
36
8
0
8
0
0
0
% Q
% Arg:
93
0
43
0
0
0
0
0
43
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% T
% Val:
0
0
0
79
0
8
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _