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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADCK4
All Species:
31.52
Human Site:
S76
Identified Species:
53.33
UniProt:
Q96D53
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96D53
NP_001136027.1
544
60069
S76
K
T
P
R
P
Q
L
S
D
R
S
R
E
R
K
Chimpanzee
Pan troglodytes
XP_512672
501
55211
G64
G
L
L
R
G
N
G
G
Q
L
G
Q
T
X
X
Rhesus Macaque
Macaca mulatta
XP_001097315
544
59987
S76
K
T
P
R
L
Q
L
S
D
R
S
R
E
R
K
Dog
Lupus familis
XP_541612
484
54091
S76
K
T
S
R
P
Q
L
S
D
R
S
R
E
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q566J8
533
59213
S77
K
A
P
R
P
Q
L
S
D
R
S
R
E
R
K
Rat
Rattus norvegicus
Q6AY19
528
58886
S77
K
A
P
R
P
Q
L
S
D
R
S
R
E
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517948
515
57559
R62
L
S
E
R
A
R
E
R
R
V
P
A
S
R
L
Chicken
Gallus gallus
XP_415040
648
72471
S196
K
P
Y
K
Q
M
L
S
E
R
A
R
E
R
K
Frog
Xenopus laevis
NP_001087459
560
63668
S103
R
Y
K
Q
Q
K
L
S
D
R
A
R
E
R
K
Zebra Danio
Brachydanio rerio
Q5RGU1
602
66969
S166
K
P
H
K
Q
M
L
S
E
R
A
R
E
R
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624948
466
53616
T57
V
G
T
V
A
E
Y
T
R
R
T
F
G
L
K
Nematode Worm
Caenorhab. elegans
Q18486
755
83597
L298
E
M
G
N
V
H
T
L
T
R
S
N
E
S
S
Sea Urchin
Strong. purpuratus
XP_791783
633
70501
S189
P
R
V
K
P
T
L
S
A
Q
A
K
E
K
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P27697
501
56723
K62
R
K
H
E
E
E
K
K
D
T
L
K
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
96.5
81.4
N.A.
85.2
82.7
N.A.
70.7
50.6
58.3
50.6
N.A.
N.A.
44.6
34.5
46.9
Protein Similarity:
100
84
97.4
84.9
N.A.
89.7
88.5
N.A.
78.4
63.4
70.7
63.9
N.A.
N.A.
62.3
47.8
60.5
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
53.3
53.3
53.3
N.A.
N.A.
13.3
20
26.6
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
93.3
N.A.
26.6
73.3
80
73.3
N.A.
N.A.
33.3
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
15
0
0
0
8
0
29
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% D
% Glu:
8
0
8
8
8
15
8
0
15
0
0
0
72
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
8
8
0
8
0
8
8
0
0
8
0
8
0
0
% G
% His:
0
0
15
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
50
8
8
22
0
8
8
8
0
0
0
15
0
8
65
% K
% Leu:
8
8
8
0
8
0
65
8
0
8
8
0
0
8
8
% L
% Met:
0
8
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
8
15
29
0
36
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
22
36
0
0
8
8
0
8
0
0
0
% Q
% Arg:
15
8
0
50
0
8
0
8
15
72
0
58
0
65
0
% R
% Ser:
0
8
8
0
0
0
0
65
0
0
43
0
15
15
15
% S
% Thr:
0
22
8
0
0
8
8
8
8
8
8
0
8
0
0
% T
% Val:
8
0
8
8
8
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _