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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ADCK4 All Species: 31.21
Human Site: S90 Identified Species: 52.82
UniProt: Q96D53 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96D53 NP_001136027.1 544 60069 S90 K V P A S R I S R L A N F G G
Chimpanzee Pan troglodytes XP_512672 501 55211 G78 X R P C G A L G L G G G S G L
Rhesus Macaque Macaca mulatta XP_001097315 544 59987 S90 K V P A S R I S R L A N F G G
Dog Lupus familis XP_541612 484 54091 S90 K V P A S R I S R L A N F G G
Cat Felis silvestris
Mouse Mus musculus Q566J8 533 59213 S91 K V P A S R I S R L A S F G G
Rat Rattus norvegicus Q6AY19 528 58886 S91 K V P A S R I S R L A S F G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517948 515 57559 G76 L S R L A N F G G L A V G L G
Chicken Gallus gallus XP_415040 648 72471 G210 K V P V T R I G R L A N F G G
Frog Xenopus laevis NP_001087459 560 63668 S117 K V P A S R I S R L A N F G G
Zebra Danio Brachydanio rerio Q5RGU1 602 66969 G180 K V P V T R L G R L A N F G G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624948 466 53616 T71 K K Q S L G N T F D N L F L T
Nematode Worm Caenorhab. elegans Q18486 755 83597 G312 S V P A T R I G R L A T F G Q
Sea Urchin Strong. purpuratus XP_791783 633 70501 S203 A V P A S R M S R V L N F G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P27697 501 56723 S76 S V P T S R I S R L F H Y G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 81.8 96.5 81.4 N.A. 85.2 82.7 N.A. 70.7 50.6 58.3 50.6 N.A. N.A. 44.6 34.5 46.9
Protein Similarity: 100 84 97.4 84.9 N.A. 89.7 88.5 N.A. 78.4 63.4 70.7 63.9 N.A. N.A. 62.3 47.8 60.5
P-Site Identity: 100 13.3 100 100 N.A. 93.3 93.3 N.A. 20 80 100 73.3 N.A. N.A. 13.3 66.6 73.3
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 26.6 86.6 100 86.6 N.A. N.A. 26.6 73.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 53.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 58 8 8 0 0 0 0 72 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 8 0 8 0 79 0 0 % F
% Gly: 0 0 0 0 8 8 0 36 8 8 8 8 8 86 72 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 65 0 0 0 0 0 0 0 0 % I
% Lys: 65 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 0 8 8 0 15 0 8 79 8 8 0 15 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 0 0 0 8 50 0 0 0 % N
% Pro: 0 0 86 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 8 0 0 79 0 0 79 0 0 0 0 0 0 % R
% Ser: 15 8 0 8 58 0 0 58 0 0 0 15 8 0 8 % S
% Thr: 0 0 0 8 22 0 0 8 0 0 0 8 0 0 8 % T
% Val: 0 79 0 15 0 0 0 0 0 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _