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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C19orf22 All Species: 16.36
Human Site: S42 Identified Species: 40
UniProt: Q96D70 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96D70 NP_620129.2 268 30350 S42 S S Q V K R L S A S R R K Q H
Chimpanzee Pan troglodytes XP_001172153 344 38053 R118 A E G T P G G R R L L R K Q H
Rhesus Macaque Macaca mulatta XP_001092673 268 30305 S42 S S Q V K R L S A S R R K Q H
Dog Lupus familis XP_855200 281 31121 S62 G S Q V K R L S A S K R K Q H
Cat Felis silvestris
Mouse Mus musculus Q4VBF2 262 29641 S39 G S Q V K R V S A S R R K Q H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514745 109 12717
Chicken Gallus gallus XP_001233902 215 24629
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001074116 254 29146 S33 S S P A K R V S P A K K K Q F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001197403 266 30157 R38 T S F S N S P R R K K K T G I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_563680 245 27701 R26 R G D T S V S R G L S L E K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.9 97.7 80.4 N.A. 84.3 N.A. N.A. 30.2 52.6 N.A. 51.1 N.A. N.A. N.A. N.A. 28.3
Protein Similarity: 100 71.8 98.1 83.9 N.A. 89.9 N.A. N.A. 36.1 63.4 N.A. 65.6 N.A. N.A. N.A. N.A. 46.2
P-Site Identity: 100 26.6 100 86.6 N.A. 86.6 N.A. N.A. 0 0 N.A. 46.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 33.3 100 93.3 N.A. 93.3 N.A. N.A. 0 0 N.A. 73.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 25.3 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 0 0 40 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 0 0 10 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 20 10 10 0 0 10 10 0 10 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 0 0 50 0 0 0 0 10 30 20 60 10 10 % K
% Leu: 0 0 0 0 0 0 30 0 0 20 10 10 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 0 10 0 10 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 40 0 0 0 0 0 0 0 0 0 0 60 0 % Q
% Arg: 10 0 0 0 0 50 0 30 20 0 30 50 0 0 0 % R
% Ser: 30 60 0 10 10 10 10 50 0 40 10 0 0 0 0 % S
% Thr: 10 0 0 20 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 0 0 0 40 0 10 20 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _