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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: REPS1 All Species: 16.97
Human Site: S377 Identified Species: 53.33
UniProt: Q96D71 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96D71 NP_001122089.1 796 86662 S377 K L I D L E D S A D V G D Q P
Chimpanzee Pan troglodytes XP_518769 795 86562 S377 K L I D L E D S A D V G D Q P
Rhesus Macaque Macaca mulatta XP_001094536 768 83689 V350 F C A A F H L V V A R K N G Y
Dog Lupus familis XP_533426 744 80805 S325 K L I D L E D S A D V G D Q P
Cat Felis silvestris
Mouse Mus musculus O54916 795 86500 S377 K L I D L E D S A D V G E Q P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521447 342 37533
Chicken Gallus gallus NP_001012895 773 84817 V351 F C A A F H L V V A R K N G Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038521 790 86417 S374 K L I D L D D S A G V P E P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 95.4 91.5 N.A. 95 N.A. N.A. 40 72.8 N.A. 72.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 95.8 91.9 N.A. 96.8 N.A. N.A. 41.3 80.2 N.A. 81.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 100 N.A. 93.3 N.A. N.A. 0 0 N.A. 60 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 6.6 100 N.A. 100 N.A. N.A. 0 6.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 25 25 0 0 0 0 63 25 0 0 0 0 13 % A
% Cys: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 63 0 13 63 0 0 50 0 0 38 0 0 % D
% Glu: 0 0 0 0 0 50 0 0 0 0 0 0 25 0 0 % E
% Phe: 25 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 0 50 0 25 0 % G
% His: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 63 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 63 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % K
% Leu: 0 63 0 0 63 0 25 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 13 0 13 50 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 63 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 25 25 0 63 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _