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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HDAC11 All Species: 28.48
Human Site: Y79 Identified Species: 69.63
UniProt: Q96DB2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DB2 NP_079103.2 347 39183 Y79 L V V H T R R Y L N E L K W S
Chimpanzee Pan troglodytes XP_530587 530 58066 R120 V T R P A L Q R E T Q A L R A
Rhesus Macaque Macaca mulatta XP_001082767 347 39161 Y79 L V V H T R R Y L N E L K W S
Dog Lupus familis XP_541747 410 45854 Y142 L V V H T R R Y L N E L K W S
Cat Felis silvestris
Mouse Mus musculus Q91WA3 347 39139 Y79 L V V H T R R Y L N E L K W S
Rat Rattus norvegicus NP_001100080 155 17549
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414321 358 39887 Y79 L V V H T R R Y L N K L K W S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733048 343 39045 Y95 R R I H T R E Y L K S L R W S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783282 490 55016 Y186 L V A H T K Q Y I S R L K W S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q944K3 387 43786 Y137 L V V H S E N Y L N S L K S S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46 99.1 80 N.A. 92.2 38 N.A. N.A. 76.2 N.A. N.A. N.A. 49.5 N.A. N.A. 45.5
Protein Similarity: 100 53 99.7 83.1 N.A. 95 41.2 N.A. N.A. 85.4 N.A. N.A. N.A. 63.9 N.A. N.A. 55.5
P-Site Identity: 100 0 100 100 N.A. 100 0 N.A. N.A. 93.3 N.A. N.A. N.A. 53.3 N.A. N.A. 60
P-Site Similarity: 100 26.6 100 100 N.A. 100 0 N.A. N.A. 100 N.A. N.A. N.A. 66.6 N.A. N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. 51.1 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 62.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 10 0 10 0 40 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 80 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 10 10 0 70 0 0 % K
% Leu: 70 0 0 0 0 10 0 0 70 0 0 80 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 60 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 20 0 0 0 10 0 0 0 0 % Q
% Arg: 10 10 10 0 0 60 50 10 0 0 10 0 10 10 0 % R
% Ser: 0 0 0 0 10 0 0 0 0 10 20 0 0 10 80 % S
% Thr: 0 10 0 0 70 0 0 0 0 10 0 0 0 0 0 % T
% Val: 10 70 60 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 0 % W
% Tyr: 0 0 0 0 0 0 0 80 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _