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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMCO6
All Species:
16.06
Human Site:
S138
Identified Species:
35.33
UniProt:
Q96DC7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC7
NP_060972.3
493
54442
S138
C
L
H
E
L
S
H
S
E
Q
S
T
V
A
E
Chimpanzee
Pan troglodytes
XP_001140277
499
54881
S138
C
L
H
E
L
S
H
S
E
Q
S
T
V
A
E
Rhesus Macaque
Macaca mulatta
XP_001087591
253
27737
Dog
Lupus familis
XP_544291
434
47389
T113
F
I
E
L
C
L
Y
T
L
G
N
L
I
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQX5
494
54897
S138
C
L
H
E
L
S
H
S
E
Q
S
A
V
A
E
Rat
Rattus norvegicus
Q56R16
536
60281
N136
F
V
K
F
L
E
R
N
E
N
C
T
L
Q
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518187
529
57507
A164
M
Q
R
L
L
R
A
A
Q
R
G
T
G
E
K
Chicken
Gallus gallus
Q5ZML1
538
60176
K138
F
V
E
F
L
K
R
K
E
N
C
T
L
Q
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q503E9
536
59774
S136
F
V
E
F
L
R
R
S
D
N
C
T
L
Q
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524167
543
59991
S149
F
V
T
F
L
R
N
S
A
N
A
T
L
Q
F
Honey Bee
Apis mellifera
XP_393050
530
58695
T148
L
T
N
I
A
S
G
T
S
Q
Q
T
R
V
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
50.7
78.3
N.A.
83.1
21.6
N.A.
34
22.1
N.A.
22
N.A.
22.6
21.3
N.A.
N.A.
Protein Similarity:
100
98.5
51.1
81.9
N.A.
89.8
38.8
N.A.
48
38.6
N.A.
39.5
N.A.
37
38.1
N.A.
N.A.
P-Site Identity:
100
100
0
6.6
N.A.
93.3
20
N.A.
13.3
20
N.A.
20
N.A.
20
20
N.A.
N.A.
P-Site Similarity:
100
100
0
40
N.A.
93.3
40
N.A.
40
33.3
N.A.
40
N.A.
46.6
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
10
10
0
10
10
0
28
0
% A
% Cys:
28
0
0
0
10
0
0
0
0
0
28
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
28
28
0
10
0
0
46
0
0
0
0
10
37
% E
% Phe:
46
0
0
37
0
0
0
0
0
0
0
0
0
0
37
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
10
0
10
0
0
% G
% His:
0
0
28
0
0
0
28
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
10
% K
% Leu:
10
28
0
19
73
10
0
0
10
0
0
10
37
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
10
0
37
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
37
10
0
0
37
0
% Q
% Arg:
0
0
10
0
0
28
28
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
37
0
46
10
0
28
0
0
0
0
% S
% Thr:
0
10
10
0
0
0
0
19
0
0
0
73
0
0
0
% T
% Val:
0
37
0
0
0
0
0
0
0
0
0
0
28
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _