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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC3
All Species:
16.36
Human Site:
S62
Identified Species:
30
UniProt:
Q96DC8
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC8
NP_078969.2
303
32694
S62
G
I
R
N
I
V
L
S
N
P
K
K
R
N
T
Chimpanzee
Pan troglodytes
XP_507654
356
38113
S115
T
R
R
N
I
V
L
S
N
P
K
K
R
N
A
Rhesus Macaque
Macaca mulatta
XP_001082412
303
32666
S62
G
I
R
N
I
V
L
S
N
P
K
K
R
N
A
Dog
Lupus familis
XP_544259
261
28483
M35
R
N
A
L
S
L
A
M
L
K
S
L
Q
T
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7J9
300
32384
S62
G
I
R
N
I
V
L
S
N
P
R
R
R
N
A
Rat
Rattus norvegicus
Q3MIE0
300
32367
S62
G
I
R
N
I
V
L
S
N
P
R
R
R
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515815
544
57988
N59
G
I
R
N
I
I
L
N
N
P
K
K
R
N
A
Chicken
Gallus gallus
XP_417287
290
31195
A53
N
N
P
G
R
R
N
A
L
S
L
S
M
L
Q
Frog
Xenopus laevis
A9JS71
294
32171
N55
G
I
R
R
I
I
L
N
N
P
Q
Q
R
N
A
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
L53
N
P
R
K
R
N
A
L
S
L
Q
M
L
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623935
309
35061
N66
G
V
R
T
L
I
L
N
H
L
P
S
R
N
S
Nematode Worm
Caenorhab. elegans
P34559
288
31153
P53
A
L
I
K
L
N
R
P
K
A
L
N
A
L
C
Sea Urchin
Strong. purpuratus
XP_001202186
273
29376
E47
M
L
T
E
V
T
K
E
L
T
R
D
V
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
96.3
71.9
N.A.
81.5
80.8
N.A.
40
64.6
63.3
57
N.A.
N.A.
43.6
28.3
50.5
Protein Similarity:
100
83.9
98
79.2
N.A.
87.7
86.4
N.A.
44.1
77.2
75.5
71.6
N.A.
N.A.
63.4
47.1
64.6
P-Site Identity:
100
80
93.3
0
N.A.
80
80
N.A.
80
0
60
6.6
N.A.
N.A.
33.3
0
0
P-Site Similarity:
100
80
93.3
13.3
N.A.
93.3
93.3
N.A.
93.3
6.6
86.6
26.6
N.A.
N.A.
73.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
16
8
0
8
0
0
8
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% D
% Glu:
0
0
0
8
0
0
0
8
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
54
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
47
8
0
54
24
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
16
0
0
8
0
8
8
31
31
0
0
0
% K
% Leu:
0
16
0
8
16
8
62
8
24
16
16
8
8
16
0
% L
% Met:
8
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% M
% Asn:
16
16
0
47
0
16
8
24
54
0
0
8
0
62
0
% N
% Pro:
0
8
8
0
0
0
0
8
0
54
8
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
16
8
8
0
8
% Q
% Arg:
8
8
70
8
16
8
8
0
0
0
24
16
62
0
0
% R
% Ser:
0
0
0
0
8
0
0
39
8
8
8
16
0
0
16
% S
% Thr:
8
0
8
8
0
8
0
0
0
8
0
0
0
8
8
% T
% Val:
0
8
0
0
8
39
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _