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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC3
All Species:
18.18
Human Site:
S80
Identified Species:
33.33
UniProt:
Q96DC8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC8
NP_078969.2
303
32694
S80
A
M
L
K
S
L
Q
S
D
I
L
H
D
A
D
Chimpanzee
Pan troglodytes
XP_507654
356
38113
S133
A
M
L
K
S
L
Q
S
D
I
L
H
D
A
D
Rhesus Macaque
Macaca mulatta
XP_001082412
303
32666
S80
A
M
L
K
S
L
Q
S
D
I
L
H
D
A
D
Dog
Lupus familis
XP_544259
261
28483
R53
E
S
E
S
K
D
L
R
V
I
I
I
S
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7J9
300
32384
S80
A
M
L
K
S
L
R
S
D
I
L
H
E
A
E
Rat
Rattus norvegicus
Q3MIE0
300
32367
S80
A
M
L
K
S
L
R
S
D
I
L
H
E
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515815
544
57988
N77
S
M
L
N
S
L
R
N
D
I
L
H
E
A
E
Chicken
Gallus gallus
XP_417287
290
31195
K71
E
D
L
L
H
D
V
K
S
K
E
L
R
V
I
Frog
Xenopus laevis
A9JS71
294
32171
K73
P
M
I
Q
S
L
Q
K
D
I
L
H
E
A
D
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
N71
N
I
L
T
D
A
D
N
P
E
L
H
V
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623935
309
35061
K84
K
M
L
K
Y
L
W
K
N
I
V
H
D
E
N
Nematode Worm
Caenorhab. elegans
P34559
288
31153
L71
M
T
E
L
A
D
A
L
E
V
L
D
T
D
K
Sea Urchin
Strong. purpuratus
XP_001202186
273
29376
E65
R
A
I
I
I
A
S
E
G
P
V
Y
S
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
96.3
71.9
N.A.
81.5
80.8
N.A.
40
64.6
63.3
57
N.A.
N.A.
43.6
28.3
50.5
Protein Similarity:
100
83.9
98
79.2
N.A.
87.7
86.4
N.A.
44.1
77.2
75.5
71.6
N.A.
N.A.
63.4
47.1
64.6
P-Site Identity:
100
100
100
13.3
N.A.
80
80
N.A.
60
6.6
66.6
20
N.A.
N.A.
46.6
6.6
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
93.3
6.6
86.6
33.3
N.A.
N.A.
66.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
8
0
0
8
16
8
0
0
0
0
0
0
70
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
24
8
0
54
0
0
8
31
8
31
% D
% Glu:
16
0
16
0
0
0
0
8
8
8
8
0
31
8
31
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
70
0
0
0
% H
% Ile:
0
8
16
8
8
0
0
0
0
70
8
8
0
8
16
% I
% Lys:
8
0
0
47
8
0
0
24
0
8
0
0
0
0
8
% K
% Leu:
0
0
70
16
0
62
8
8
0
0
70
8
0
0
0
% L
% Met:
8
62
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
16
8
0
0
0
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
31
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
24
8
0
0
0
0
8
0
0
% R
% Ser:
8
8
0
8
54
0
8
39
8
0
0
0
16
0
0
% S
% Thr:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
8
0
8
8
16
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _