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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC3
All Species:
15.15
Human Site:
T48
Identified Species:
27.78
UniProt:
Q96DC8
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC8
NP_078969.2
303
32694
T48
R
E
S
E
P
R
P
T
S
A
R
Q
L
D
G
Chimpanzee
Pan troglodytes
XP_507654
356
38113
G101
G
G
N
S
P
C
P
G
P
G
P
G
S
E
T
Rhesus Macaque
Macaca mulatta
XP_001082412
303
32666
T48
R
E
S
E
P
R
P
T
S
A
R
Q
L
D
G
Dog
Lupus familis
XP_544259
261
28483
V21
R
D
G
I
R
N
I
V
L
S
D
P
K
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7J9
300
32384
T48
S
E
S
E
P
R
L
T
S
T
R
Q
Q
D
G
Rat
Rattus norvegicus
Q3MIE0
300
32367
T48
P
E
S
E
P
R
L
T
S
T
R
Q
Q
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515815
544
57988
T45
S
S
G
P
I
R
P
T
S
A
R
Q
R
D
G
Chicken
Gallus gallus
XP_417287
290
31195
G39
T
L
R
R
Q
S
G
G
V
R
N
I
I
L
N
Frog
Xenopus laevis
A9JS71
294
32171
T41
H
L
Q
H
T
P
L
T
V
L
Q
Q
E
H
G
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
I39
L
T
E
Q
Q
G
G
I
R
R
I
I
L
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623935
309
35061
L52
S
L
S
E
E
K
Y
L
D
V
K
E
E
N
G
Nematode Worm
Caenorhab. elegans
P34559
288
31153
V39
E
M
I
K
I
E
K
V
G
E
K
Q
N
V
A
Sea Urchin
Strong. purpuratus
XP_001202186
273
29376
R33
H
H
S
P
R
S
L
R
N
A
L
S
L
A
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
96.3
71.9
N.A.
81.5
80.8
N.A.
40
64.6
63.3
57
N.A.
N.A.
43.6
28.3
50.5
Protein Similarity:
100
83.9
98
79.2
N.A.
87.7
86.4
N.A.
44.1
77.2
75.5
71.6
N.A.
N.A.
63.4
47.1
64.6
P-Site Identity:
100
13.3
100
6.6
N.A.
73.3
73.3
N.A.
60
0
20
6.6
N.A.
N.A.
20
6.6
20
P-Site Similarity:
100
26.6
100
20
N.A.
73.3
73.3
N.A.
60
6.6
26.6
20
N.A.
N.A.
46.6
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
31
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
8
0
8
0
0
39
0
% D
% Glu:
8
31
8
39
8
8
0
0
0
8
0
8
16
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
16
0
0
8
16
16
8
8
0
8
0
0
54
% G
% His:
16
8
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
8
16
0
8
8
0
0
8
16
8
0
0
% I
% Lys:
0
0
0
8
0
8
8
0
0
0
16
0
8
8
0
% K
% Leu:
8
24
0
0
0
0
31
8
8
8
8
0
31
8
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
8
0
0
8
0
0
8
0
8
0
8
16
16
% N
% Pro:
8
0
0
16
39
8
31
0
8
0
8
8
0
0
0
% P
% Gln:
0
0
8
8
16
0
0
0
0
0
8
54
16
0
0
% Q
% Arg:
24
0
8
8
16
39
0
8
8
16
39
0
8
0
8
% R
% Ser:
24
8
47
8
0
16
0
0
39
8
0
8
8
0
0
% S
% Thr:
8
8
0
0
8
0
0
47
0
16
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
16
16
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _