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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC3
All Species:
25.15
Human Site:
Y120
Identified Species:
46.11
UniProt:
Q96DC8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC8
NP_078969.2
303
32694
Y120
T
E
E
Q
G
R
D
Y
H
A
E
V
F
Q
T
Chimpanzee
Pan troglodytes
XP_507654
356
38113
Y173
T
E
E
Q
G
R
D
Y
H
A
E
V
F
Q
T
Rhesus Macaque
Macaca mulatta
XP_001082412
303
32666
Y120
T
E
E
Q
G
R
D
Y
H
A
E
V
F
Q
T
Dog
Lupus familis
XP_544259
261
28483
M93
F
Q
T
C
S
E
V
M
M
L
I
Q
N
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7J9
300
32384
Y120
T
D
A
Q
G
R
D
Y
H
A
E
V
F
Q
T
Rat
Rattus norvegicus
Q3MIE0
300
32367
Y120
T
G
A
Q
G
R
D
Y
H
T
E
V
F
Q
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515815
544
57988
Y117
T
D
E
Q
G
P
D
Y
H
M
E
V
F
Q
T
Chicken
Gallus gallus
XP_417287
290
31195
V111
H
H
T
Q
V
F
E
V
C
A
E
V
M
T
L
Frog
Xenopus laevis
A9JS71
294
32171
Y113
T
A
E
Y
G
K
D
Y
H
M
E
V
F
N
T
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
C111
P
R
R
V
F
H
S
C
S
E
L
M
M
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623935
309
35061
L124
L
T
N
N
N
E
K
L
H
K
E
I
F
E
T
Nematode Worm
Caenorhab. elegans
P34559
288
31153
S111
N
E
F
A
T
T
F
S
G
S
F
L
S
N
W
Sea Urchin
Strong. purpuratus
XP_001202186
273
29376
P105
M
M
L
V
E
D
L
P
I
P
V
I
A
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
96.3
71.9
N.A.
81.5
80.8
N.A.
40
64.6
63.3
57
N.A.
N.A.
43.6
28.3
50.5
Protein Similarity:
100
83.9
98
79.2
N.A.
87.7
86.4
N.A.
44.1
77.2
75.5
71.6
N.A.
N.A.
63.4
47.1
64.6
P-Site Identity:
100
100
100
0
N.A.
86.6
80
N.A.
80
26.6
66.6
0
N.A.
N.A.
26.6
6.6
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
93.3
80
N.A.
86.6
33.3
73.3
6.6
N.A.
N.A.
40
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
16
8
0
0
0
0
0
39
0
0
8
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
16
0
0
0
8
54
0
0
0
0
0
0
0
0
% D
% Glu:
0
31
39
0
8
16
8
0
0
8
70
0
0
8
0
% E
% Phe:
8
0
8
0
8
8
8
0
0
0
8
0
62
0
0
% F
% Gly:
0
8
0
0
54
0
0
0
8
0
0
0
0
0
0
% G
% His:
8
8
0
0
0
8
0
0
62
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
16
0
0
8
% I
% Lys:
0
0
0
0
0
8
8
0
0
8
0
0
0
0
0
% K
% Leu:
8
0
8
0
0
0
8
8
0
8
8
8
0
8
8
% L
% Met:
8
8
0
0
0
0
0
8
8
16
0
8
16
0
0
% M
% Asn:
8
0
8
8
8
0
0
0
0
0
0
0
8
16
0
% N
% Pro:
8
0
0
0
0
8
0
8
0
8
0
0
0
0
8
% P
% Gln:
0
8
0
54
0
0
0
0
0
0
0
8
0
54
0
% Q
% Arg:
0
8
8
0
0
39
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
8
8
8
8
0
0
8
0
0
% S
% Thr:
54
8
16
0
8
8
0
0
0
8
0
0
0
8
62
% T
% Val:
0
0
0
16
8
0
8
8
0
0
8
62
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
0
54
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _