KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ECHDC3
All Species:
34.85
Human Site:
Y267
Identified Species:
63.89
UniProt:
Q96DC8
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DC8
NP_078969.2
303
32694
Y267
P
Q
D
L
G
T
A
Y
Y
L
T
S
Q
A
M
Chimpanzee
Pan troglodytes
XP_507654
356
38113
Y320
P
Q
D
L
G
T
A
Y
Y
L
T
S
Q
A
M
Rhesus Macaque
Macaca mulatta
XP_001082412
303
32666
Y267
P
Q
D
L
G
T
A
Y
Y
L
T
S
R
A
M
Dog
Lupus familis
XP_544259
261
28483
Y228
P
Q
D
L
R
T
A
Y
H
L
T
S
Q
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D7J9
300
32384
Y267
P
Q
D
L
R
T
A
Y
F
L
A
S
Q
A
M
Rat
Rattus norvegicus
Q3MIE0
300
32367
Y267
P
Q
D
L
S
T
A
Y
F
L
A
S
Q
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515815
544
57988
Y264
S
E
D
L
G
T
A
Y
R
L
T
S
Q
A
M
Chicken
Gallus gallus
XP_417287
290
31195
Y251
A
Q
D
L
D
T
A
Y
K
I
T
S
Q
V
M
Frog
Xenopus laevis
A9JS71
294
32171
Y260
A
K
S
L
T
D
A
Y
K
L
T
S
E
V
M
Zebra Danio
Brachydanio rerio
A0PJR5
289
31421
Y250
S
Q
S
R
D
A
A
Y
S
T
A
G
A
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623935
309
35061
Y271
D
L
D
T
S
T
A
Y
L
L
G
T
E
K
M
Nematode Worm
Caenorhab. elegans
P34559
288
31153
L254
E
L
T
L
Q
E
G
L
H
F
E
R
R
L
F
Sea Urchin
Strong. purpuratus
XP_001202186
273
29376
M240
Y
D
H
A
S
D
V
M
V
N
N
L
S
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
96.3
71.9
N.A.
81.5
80.8
N.A.
40
64.6
63.3
57
N.A.
N.A.
43.6
28.3
50.5
Protein Similarity:
100
83.9
98
79.2
N.A.
87.7
86.4
N.A.
44.1
77.2
75.5
71.6
N.A.
N.A.
63.4
47.1
64.6
P-Site Identity:
100
100
93.3
80
N.A.
80
80
N.A.
80
66.6
46.6
33.3
N.A.
N.A.
40
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
86.6
73.3
60
33.3
N.A.
N.A.
53.3
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
0
8
85
0
0
0
24
0
8
54
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
70
0
16
16
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
8
0
0
0
0
8
0
16
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
16
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
31
0
8
0
0
0
8
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
16
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
16
0
0
0
0
8
0
% K
% Leu:
0
16
0
77
0
0
0
8
8
70
0
8
0
16
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
85
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
62
0
0
8
0
0
0
0
0
0
0
54
0
0
% Q
% Arg:
0
0
0
8
16
0
0
0
8
0
0
8
16
0
0
% R
% Ser:
16
0
16
0
24
0
0
0
8
0
0
70
8
0
0
% S
% Thr:
0
0
8
8
8
70
0
0
0
8
54
8
0
8
0
% T
% Val:
0
0
0
0
0
0
8
0
8
0
0
0
0
16
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
85
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _