KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHISA4
All Species:
14.24
Human Site:
Y172
Identified Species:
52.22
UniProt:
Q96DD7
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DD7
NP_937792.1
197
21540
Y172
P
A
P
Q
Y
P
L
Y
P
A
G
P
P
V
Y
Chimpanzee
Pan troglodytes
XP_001140118
330
35049
Y305
P
A
P
Q
Y
P
L
Y
P
A
G
P
P
V
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853493
137
14566
R113
R
R
R
Q
H
L
Q
R
P
F
E
R
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CA71
197
21465
Y172
P
A
P
Q
Y
P
L
Y
P
A
G
P
P
I
Y
Rat
Rattus norvegicus
Q5XIH2
130
13863
Y106
Q
S
T
G
P
P
A
Y
H
E
T
L
A
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508386
278
30244
Y253
P
P
A
Q
Y
P
L
Y
P
T
G
P
P
G
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
A2RV66
269
29166
Y221
M
Q
P
P
F
I
N
Y
A
V
P
A
E
H
A
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.3
N.A.
32.4
N.A.
92.3
22.3
N.A.
44.9
N.A.
23.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
59.3
N.A.
36
N.A.
94.4
32.9
N.A.
52.5
N.A.
36
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
13.3
N.A.
93.3
13.3
N.A.
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
100
20
N.A.
73.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
43
15
0
0
0
15
0
15
43
0
15
29
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
15
15
0
15
0
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
15
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
58
0
0
29
0
% G
% His:
0
0
0
0
15
0
0
0
15
0
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
15
0
0
0
0
0
0
0
15
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
15
58
0
0
0
0
15
0
0
0
% L
% Met:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% N
% Pro:
58
15
58
15
15
72
0
0
72
0
15
58
58
0
0
% P
% Gln:
15
15
0
72
0
0
15
0
0
0
0
0
0
0
0
% Q
% Arg:
15
15
15
0
0
0
0
15
0
0
0
15
0
15
0
% R
% Ser:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
15
0
0
0
0
0
0
15
15
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
15
0
0
0
29
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
58
0
0
86
0
0
0
0
0
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _