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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGCR14
All Species:
23.33
Human Site:
S417
Identified Species:
51.33
UniProt:
Q96DF8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DF8
NP_073210.1
476
52568
S417
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Chimpanzee
Pan troglodytes
XP_515236
476
52566
S417
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Rhesus Macaque
Macaca mulatta
XP_001104496
476
52530
S417
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Dog
Lupus familis
XP_543551
476
52338
S417
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Cat
Felis silvestris
Mouse
Mus musculus
O70279
479
52585
S420
T
D
R
A
L
R
A
S
Y
T
P
S
P
A
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415216
479
52576
S418
T
D
K
A
L
R
A
S
Y
T
P
S
P
A
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662300
469
52380
R410
K
Y
T
D
K
A
L
R
A
S
Y
T
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O44424
501
56001
S411
M
E
R
L
A
S
M
S
P
A
A
Q
L
L
A
Honey Bee
Apis mellifera
XP_395775
599
67859
A531
A
T
Q
K
L
R
I
A
S
T
P
T
P
R
R
Nematode Worm
Caenorhab. elegans
P34420
531
58500
P453
M
L
P
A
H
K
S
P
F
A
S
P
K
I
M
Sea Urchin
Strong. purpuratus
XP_001184722
381
41451
P323
T
P
S
L
G
G
T
P
N
R
T
P
G
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.3
94.9
N.A.
92.6
N.A.
N.A.
N.A.
71.4
N.A.
64
N.A.
32.7
30.5
26.9
39.5
Protein Similarity:
100
99.7
99.5
96.4
N.A.
95.6
N.A.
N.A.
N.A.
83.9
N.A.
79.4
N.A.
50.7
48.7
46.3
54.4
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
86.6
N.A.
6.6
N.A.
13.3
40
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
N.A.
93.3
N.A.
26.6
N.A.
20
60
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
64
10
10
55
10
10
19
10
0
0
55
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
55
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
10
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
10
0
10
10
10
10
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
19
64
0
10
0
0
0
0
0
10
10
0
% L
% Met:
19
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
10
10
0
0
0
0
19
10
0
64
19
73
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
55
0
0
64
0
10
0
10
0
0
0
10
55
% R
% Ser:
0
0
10
0
0
10
10
64
10
10
10
55
0
19
0
% S
% Thr:
64
10
10
0
0
0
10
0
0
64
10
19
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
55
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _