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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSI2 All Species: 15.45
Human Site: S16 Identified Species: 28.33
UniProt: Q96DH6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DH6 NP_620412.1 328 35197 S16 T S G S A N D S Q H D P G K M
Chimpanzee Pan troglodytes XP_001162046 324 34904 S16 T S V M F S P S S K M F I G G
Rhesus Macaque Macaca mulatta Q28521 320 34202 S32 T T D E S L R S H F E Q W G T
Dog Lupus familis XP_532379 324 34866 S16 T S V M F S P S S K M F I G G
Cat Felis silvestris
Mouse Mus musculus Q920Q6 346 36920 S16 T S G S A N D S Q H D P G K M
Rat Rattus norvegicus Q8K3P4 362 39115 P16 G L A S P D S P H D P C K M F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506312 349 37295 S16 T S V M F S S S S K M F I G G
Chicken Gallus gallus Q5ZI72 301 33425 S18 A E E F A E G S K I N A S K N
Frog Xenopus laevis Q7ZX83 293 32595 F10 G F G A A P D F N E G S K I N
Zebra Danio Brachydanio rerio NP_997961 388 41982 S16 T S G S L N D S Q H D P G K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVE5 369 40069 V24 G P C S P S E V P N D P G K M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 E18 G S G D A S L E P E N L R K I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 L154 E E R S K A D L S K E S C K M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 30.1 92.6 N.A. 94.5 70.4 N.A. 88.2 37.2 37.5 78.6 N.A. 56.3 N.A. 30.9 N.A.
Protein Similarity: 100 95.1 46.9 94.8 N.A. 94.5 76.8 N.A. 88.8 49.3 48.1 80.6 N.A. 65.5 N.A. 46.8 N.A.
P-Site Identity: 100 20 13.3 20 N.A. 100 6.6 N.A. 20 20 20 93.3 N.A. 40 N.A. 26.6 N.A.
P-Site Similarity: 100 26.6 33.3 26.6 N.A. 100 13.3 N.A. 26.6 33.3 26.6 93.3 N.A. 60 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 39 8 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 8 8 0 0 % C
% Asp: 0 0 8 8 0 8 39 0 0 8 31 0 0 0 0 % D
% Glu: 8 16 8 8 0 8 8 8 0 16 16 0 0 0 0 % E
% Phe: 0 8 0 8 24 0 0 8 0 8 0 24 0 0 8 % F
% Gly: 31 0 39 0 0 0 8 0 0 0 8 0 31 31 24 % G
% His: 0 0 0 0 0 0 0 0 16 24 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 24 8 8 % I
% Lys: 0 0 0 0 8 0 0 0 8 31 0 0 16 54 0 % K
% Leu: 0 8 0 0 8 8 8 8 0 0 0 8 0 0 0 % L
% Met: 0 0 0 24 0 0 0 0 0 0 24 0 0 8 39 % M
% Asn: 0 0 0 0 0 24 0 0 8 8 16 0 0 0 16 % N
% Pro: 0 8 0 0 16 8 16 8 16 0 8 31 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 24 0 0 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 8 0 0 0 0 0 8 0 0 % R
% Ser: 0 54 0 47 8 39 16 62 31 0 0 16 8 0 0 % S
% Thr: 54 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % T
% Val: 0 0 24 0 0 0 0 8 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _