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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MSI2 All Species: 15.76
Human Site: S308 Identified Species: 28.89
UniProt: Q96DH6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DH6 NP_620412.1 328 35197 S308 A A S P Q P G S G F G H G I A
Chimpanzee Pan troglodytes XP_001162046 324 34904 S304 A A S P Q P G S G F G H G I A
Rhesus Macaque Macaca mulatta Q28521 320 34202 N301 Q Y F A K P R N Q G G Y G G S
Dog Lupus familis XP_532379 324 34866 S304 A A S P Q P G S G F G H G I A
Cat Felis silvestris
Mouse Mus musculus Q920Q6 346 36920 S308 A D L Y G P A S Q D S G V G N
Rat Rattus norvegicus Q8K3P4 362 39115 T342 A A S P A P S T G F G H S L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506312 349 37295 A304 G P V A A T P A D L Y G P A S
Chicken Gallus gallus Q5ZI72 301 33425 S282 T D Y S G Q Q S T Y G K A S R
Frog Xenopus laevis Q7ZX83 293 32595 Q274 Y T E Y S G Q Q S T Y G K A R
Zebra Danio Brachydanio rerio NP_997961 388 41982 N308 E H V T S T C N S P S Q H H P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVE5 369 40069 P346 S P Q P S G F P I A V S R A P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 W327 Q G Q Q Q G G W G G Q S G A Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 S462 T S N T D S G S P P L N L P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 30.1 92.6 N.A. 94.5 70.4 N.A. 88.2 37.2 37.5 78.6 N.A. 56.3 N.A. 30.9 N.A.
Protein Similarity: 100 95.1 46.9 94.8 N.A. 94.5 76.8 N.A. 88.8 49.3 48.1 80.6 N.A. 65.5 N.A. 46.8 N.A.
P-Site Identity: 100 100 20 100 N.A. 20 60 N.A. 0 13.3 0 0 N.A. 6.6 N.A. 26.6 N.A.
P-Site Similarity: 100 100 46.6 100 N.A. 20 73.3 N.A. 13.3 20 0 6.6 N.A. 13.3 N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 26 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 39 31 0 16 16 0 8 8 0 8 0 0 8 31 24 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 16 0 0 8 0 0 0 8 8 0 0 0 0 0 % D
% Glu: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 8 0 0 31 0 0 0 0 0 % F
% Gly: 8 8 0 0 16 24 39 0 39 16 47 24 39 16 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 31 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 24 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 8 8 0 0 % K
% Leu: 0 0 8 0 0 0 0 0 0 8 8 0 8 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 0 0 0 16 0 0 0 8 0 0 16 % N
% Pro: 0 16 0 39 0 47 8 8 8 16 0 0 8 8 16 % P
% Gln: 16 0 16 8 31 8 16 8 16 0 8 8 0 0 8 % Q
% Arg: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 16 % R
% Ser: 8 8 31 8 24 8 8 47 16 0 16 16 8 8 16 % S
% Thr: 16 8 0 16 0 16 0 8 8 8 0 0 0 0 0 % T
% Val: 0 0 16 0 0 0 0 0 0 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 8 8 8 16 0 0 0 0 0 8 16 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _