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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI2
All Species:
36.36
Human Site:
T157
Identified Species:
66.67
UniProt:
Q96DH6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DH6
NP_620412.1
328
35197
T157
H
R
G
F
G
F
V
T
F
E
N
E
D
V
V
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
T153
H
R
G
F
G
F
V
T
F
E
N
E
D
V
V
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
T169
I
V
I
Q
K
Y
H
T
V
N
G
H
N
C
E
Dog
Lupus familis
XP_532379
324
34866
T153
H
R
G
F
G
F
V
T
F
E
N
E
D
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q6
346
36920
T157
H
R
G
F
G
F
V
T
F
E
N
E
D
V
V
Rat
Rattus norvegicus
Q8K3P4
362
39115
T156
H
R
G
F
G
F
V
T
F
E
S
E
D
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
T153
H
R
G
F
G
F
V
T
F
E
N
E
D
V
V
Chicken
Gallus gallus
Q5ZI72
301
33425
R155
M
D
T
K
T
N
E
R
R
G
F
C
F
I
T
Frog
Xenopus laevis
Q7ZX83
293
32595
K147
I
E
L
P
I
D
T
K
T
N
E
R
R
G
F
Zebra Danio
Brachydanio rerio
NP_997961
388
41982
T157
H
R
G
F
G
F
V
T
F
E
N
E
D
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
T165
H
R
G
F
G
F
V
T
F
Q
S
E
D
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
T161
P
R
G
F
G
F
V
T
F
D
D
H
D
S
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
K312
F
I
D
F
K
D
R
K
I
E
I
K
R
A
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
30.1
92.6
N.A.
94.5
70.4
N.A.
88.2
37.2
37.5
78.6
N.A.
56.3
N.A.
30.9
N.A.
Protein Similarity:
100
95.1
46.9
94.8
N.A.
94.5
76.8
N.A.
88.8
49.3
48.1
80.6
N.A.
65.5
N.A.
46.8
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
86.6
N.A.
100
0
0
93.3
N.A.
86.6
N.A.
66.6
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
100
6.6
0
100
N.A.
100
N.A.
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
0
8
8
0
0
16
0
0
0
8
8
0
70
0
0
% D
% Glu:
0
8
0
0
0
0
8
0
0
62
8
62
0
0
16
% E
% Phe:
8
0
0
77
0
70
0
0
70
0
8
0
8
0
8
% F
% Gly:
0
0
70
0
70
0
0
0
0
8
8
0
0
8
0
% G
% His:
62
0
0
0
0
0
8
0
0
0
0
16
0
0
0
% H
% Ile:
16
8
8
0
8
0
0
0
8
0
8
0
0
24
0
% I
% Lys:
0
0
0
8
16
0
0
16
0
0
0
8
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
16
47
0
8
0
0
% N
% Pro:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
70
0
0
0
0
8
8
8
0
0
8
16
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
16
0
0
8
0
% S
% Thr:
0
0
8
0
8
0
8
77
8
0
0
0
0
0
8
% T
% Val:
0
8
0
0
0
0
70
0
8
0
0
0
0
47
70
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _