KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI2
All Species:
22.73
Human Site:
T58
Identified Species:
41.67
UniProt:
Q96DH6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DH6
NP_620412.1
328
35197
T58
M
V
M
R
D
P
T
T
K
R
S
R
G
F
G
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
R58
D
P
T
T
K
R
S
R
G
F
G
F
V
T
F
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
A74
K
V
D
A
A
M
N
A
R
P
H
K
V
D
G
Dog
Lupus familis
XP_532379
324
34866
R58
N
P
P
T
K
R
S
R
G
F
G
F
V
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q6
346
36920
T58
M
V
M
R
D
P
T
T
K
R
S
R
G
F
G
Rat
Rattus norvegicus
Q8K3P4
362
39115
K58
V
M
R
D
P
L
T
K
R
S
R
G
F
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
R58
D
P
T
T
K
R
S
R
G
F
G
F
V
T
F
Chicken
Gallus gallus
Q5ZI72
301
33425
T60
F
G
E
V
V
D
C
T
I
K
T
D
P
V
T
Frog
Xenopus laevis
Q7ZX83
293
32595
V52
Y
L
S
R
F
G
E
V
L
D
C
T
I
K
T
Zebra Danio
Brachydanio rerio
NP_997961
388
41982
T58
M
V
M
R
D
P
T
T
K
R
S
R
G
F
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
T66
M
V
M
K
D
P
T
T
R
R
S
R
G
F
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
T60
I
V
M
R
D
P
T
T
K
R
S
R
G
F
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
T196
K
I
M
K
D
P
A
T
G
R
S
R
G
F
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
30.1
92.6
N.A.
94.5
70.4
N.A.
88.2
37.2
37.5
78.6
N.A.
56.3
N.A.
30.9
N.A.
Protein Similarity:
100
95.1
46.9
94.8
N.A.
94.5
76.8
N.A.
88.8
49.3
48.1
80.6
N.A.
65.5
N.A.
46.8
N.A.
P-Site Identity:
100
0
13.3
0
N.A.
100
6.6
N.A.
0
6.6
6.6
100
N.A.
86.6
N.A.
93.3
N.A.
P-Site Similarity:
100
6.6
26.6
6.6
N.A.
100
26.6
N.A.
6.6
20
13.3
100
N.A.
100
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% C
% Asp:
16
0
8
8
47
8
0
0
0
8
0
8
0
8
0
% D
% Glu:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
8
0
0
0
0
24
0
24
8
47
31
% F
% Gly:
0
8
0
0
0
8
0
0
31
0
24
8
47
8
54
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
8
0
0
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
16
0
0
16
24
0
0
8
31
8
0
8
0
8
0
% K
% Leu:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% L
% Met:
31
8
47
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
24
8
0
8
47
0
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
39
0
24
0
24
24
47
8
47
0
0
0
% R
% Ser:
0
0
8
0
0
0
24
0
0
8
47
0
0
0
0
% S
% Thr:
0
0
16
24
0
0
47
54
0
0
8
8
0
24
16
% T
% Val:
8
47
0
8
8
0
0
8
0
0
0
0
31
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _