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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI2
All Species:
12.12
Human Site:
T90
Identified Species:
22.22
UniProt:
Q96DH6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DH6
NP_620412.1
328
35197
T90
H
H
E
L
D
S
K
T
I
D
P
K
V
A
F
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
K90
D
S
K
T
I
D
P
K
V
A
F
P
R
R
A
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
K106
G
A
H
L
T
V
K
K
I
F
V
G
G
I
K
Dog
Lupus familis
XP_532379
324
34866
K90
D
S
K
T
I
D
P
K
V
A
F
P
R
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q6
346
36920
T90
H
H
E
L
D
S
K
T
I
D
P
K
V
A
F
Rat
Rattus norvegicus
Q8K3P4
362
39115
I90
H
E
L
D
S
K
T
I
D
P
K
V
A
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
K90
D
S
K
T
I
D
P
K
V
A
F
P
R
R
A
Chicken
Gallus gallus
Q5ZI72
301
33425
E92
E
K
V
L
E
L
K
E
H
K
L
D
G
K
L
Frog
Xenopus laevis
Q7ZX83
293
32595
L84
A
V
S
V
D
K
V
L
E
T
N
E
H
K
L
Zebra Danio
Brachydanio rerio
NP_997961
388
41982
T90
H
H
E
L
D
S
K
T
I
D
P
K
V
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
K98
T
H
E
L
D
G
K
K
V
D
P
K
V
A
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
T92
P
H
I
I
D
G
K
T
V
D
P
K
R
A
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
I228
H
I
L
D
G
K
V
I
D
P
K
R
A
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
30.1
92.6
N.A.
94.5
70.4
N.A.
88.2
37.2
37.5
78.6
N.A.
56.3
N.A.
30.9
N.A.
Protein Similarity:
100
95.1
46.9
94.8
N.A.
94.5
76.8
N.A.
88.8
49.3
48.1
80.6
N.A.
65.5
N.A.
46.8
N.A.
P-Site Identity:
100
0
20
0
N.A.
100
6.6
N.A.
0
13.3
6.6
100
N.A.
73.3
N.A.
53.3
N.A.
P-Site Similarity:
100
13.3
20
13.3
N.A.
100
6.6
N.A.
13.3
20
20
100
N.A.
80
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
0
0
0
24
0
0
16
39
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
16
47
24
0
0
16
39
0
8
0
0
0
% D
% Glu:
8
8
31
0
8
0
0
8
8
0
0
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
24
0
0
8
31
% F
% Gly:
8
0
0
0
8
16
0
0
0
0
0
8
16
0
0
% G
% His:
39
39
8
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
8
8
8
24
0
0
16
31
0
0
0
0
16
0
% I
% Lys:
0
8
24
0
0
24
54
39
0
8
16
39
0
16
8
% K
% Leu:
0
0
16
47
0
8
0
8
0
0
8
0
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
24
0
0
16
39
24
0
0
16
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
8
31
24
0
% R
% Ser:
0
24
8
0
8
24
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
24
8
0
8
31
0
8
0
0
0
0
0
% T
% Val:
0
8
8
8
0
8
16
0
39
0
8
8
31
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _