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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI2
All Species:
19.39
Human Site:
Y129
Identified Species:
35.56
UniProt:
Q96DH6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DH6
NP_620412.1
328
35197
Y129
V
V
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
E127
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
E
D
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
G143
I
M
T
D
R
G
S
G
K
K
R
G
F
A
F
Dog
Lupus familis
XP_532379
324
34866
E127
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q6
346
36920
Y129
V
V
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
Rat
Rattus norvegicus
Q8K3P4
362
39115
Y128
T
V
E
D
V
K
H
Y
F
E
Q
F
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
E127
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
E
D
Chicken
Gallus gallus
Q5ZI72
301
33425
E129
L
S
P
D
T
S
E
E
Q
I
K
E
Y
F
G
Frog
Xenopus laevis
Q7ZX83
293
32595
E121
F
V
G
G
L
S
P
E
T
T
E
E
Q
I
K
Zebra Danio
Brachydanio rerio
NP_997961
388
41982
Y129
V
V
E
D
V
K
Q
Y
F
E
Q
F
G
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
Y137
T
L
E
D
V
K
S
Y
F
E
Q
F
G
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
Y133
T
E
D
M
L
T
E
Y
F
T
K
Y
G
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
Q282
M
L
D
K
D
T
G
Q
S
R
G
F
G
F
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
30.1
92.6
N.A.
94.5
70.4
N.A.
88.2
37.2
37.5
78.6
N.A.
56.3
N.A.
30.9
N.A.
Protein Similarity:
100
95.1
46.9
94.8
N.A.
94.5
76.8
N.A.
88.8
49.3
48.1
80.6
N.A.
65.5
N.A.
46.8
N.A.
P-Site Identity:
100
0
6.6
0
N.A.
100
86.6
N.A.
0
6.6
6.6
100
N.A.
66.6
N.A.
26.6
N.A.
P-Site Similarity:
100
6.6
33.3
6.6
N.A.
100
86.6
N.A.
6.6
26.6
20
100
N.A.
80
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
24
16
54
8
0
0
0
0
0
0
0
0
0
24
% D
% Glu:
24
8
39
0
0
0
16
39
0
39
8
16
0
24
0
% E
% Phe:
8
0
0
0
0
0
24
0
47
24
0
47
8
16
8
% F
% Gly:
0
0
8
8
0
8
8
8
0
0
31
8
54
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
8
8
% I
% Lys:
0
0
0
31
0
39
0
0
8
8
16
24
0
31
8
% K
% Leu:
8
16
0
0
16
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
24
0
24
8
31
0
39
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% R
% Ser:
0
8
0
0
0
16
16
0
8
0
0
0
0
0
0
% S
% Thr:
24
0
8
0
8
16
0
0
8
16
0
0
0
8
0
% T
% Val:
24
39
24
0
39
0
0
0
0
0
0
0
24
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
24
0
47
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _