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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSI2
All Species:
22.73
Human Site:
Y239
Identified Species:
41.67
UniProt:
Q96DH6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DH6
NP_620412.1
328
35197
Y239
G
F
A
P
S
Y
G
Y
Q
F
P
G
F
P
A
Chimpanzee
Pan troglodytes
XP_001162046
324
34904
Y235
G
F
A
P
S
Y
G
Y
Q
F
P
G
F
P
A
Rhesus Macaque
Macaca mulatta
Q28521
320
34202
R232
R
G
G
F
G
G
S
R
G
G
G
G
Y
G
G
Dog
Lupus familis
XP_532379
324
34866
Y235
G
F
A
P
S
Y
G
Y
Q
F
P
G
F
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q920Q6
346
36920
Y239
G
F
A
P
S
Y
G
Y
Q
F
P
G
F
P
A
Rat
Rattus norvegicus
Q8K3P4
362
39115
M273
P
L
T
A
Y
G
P
M
A
A
A
A
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506312
349
37295
Y235
G
F
A
P
S
Y
S
Y
Q
F
P
G
F
P
A
Chicken
Gallus gallus
Q5ZI72
301
33425
G213
G
K
S
N
A
S
G
G
R
G
G
G
R
G
R
Frog
Xenopus laevis
Q7ZX83
293
32595
G205
K
Q
Q
R
G
G
R
G
A
V
T
G
R
G
G
Zebra Danio
Brachydanio rerio
NP_997961
388
41982
Y239
G
F
S
P
S
Y
S
Y
Q
F
P
G
F
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVE5
369
40069
S277
P
L
L
T
Q
A
L
S
V
M
N
N
Y
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
G258
G
Y
G
G
D
Y
G
G
G
W
G
Q
Q
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
M393
Q
M
Q
K
Q
T
G
M
D
Y
T
Q
M
Y
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
30.1
92.6
N.A.
94.5
70.4
N.A.
88.2
37.2
37.5
78.6
N.A.
56.3
N.A.
30.9
N.A.
Protein Similarity:
100
95.1
46.9
94.8
N.A.
94.5
76.8
N.A.
88.8
49.3
48.1
80.6
N.A.
65.5
N.A.
46.8
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
6.6
N.A.
93.3
20
6.6
86.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
100
6.6
N.A.
93.3
40
6.6
93.3
N.A.
13.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
39
8
8
8
0
0
16
8
8
8
8
8
62
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
47
0
8
0
0
0
0
0
47
0
0
47
0
0
% F
% Gly:
62
8
16
8
16
24
54
24
16
16
24
70
0
31
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
8
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
8
0
0
0
0
0
16
0
8
0
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
16
0
0
47
0
0
8
0
0
0
47
0
0
47
0
% P
% Gln:
8
8
16
0
16
0
0
0
47
0
0
16
8
8
8
% Q
% Arg:
8
0
0
8
0
0
8
8
8
0
0
0
16
0
8
% R
% Ser:
0
0
16
0
47
8
24
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
8
0
8
0
0
0
0
16
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
54
0
47
0
8
0
0
16
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _