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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERP27
All Species:
9.09
Human Site:
S254
Identified Species:
18.18
UniProt:
Q96DN0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DN0
NP_689534.1
273
30480
S254
N
F
C
D
G
F
L
S
G
K
L
L
K
E
N
Chimpanzee
Pan troglodytes
XP_001158430
273
30514
S254
N
F
C
D
G
F
L
S
G
K
L
L
K
E
N
Rhesus Macaque
Macaca mulatta
XP_001090991
273
30617
S254
N
F
C
D
G
F
L
S
G
K
L
L
K
E
N
Dog
Lupus familis
XP_543794
298
33347
K254
N
F
C
D
G
F
L
K
G
K
R
L
T
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8U3
272
30675
K254
G
F
C
E
G
F
L
K
G
L
L
Q
R
D
H
Rat
Rattus norvegicus
P04785
509
56933
L349
T
Q
F
C
H
H
F
L
E
G
K
I
K
P
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510301
118
12818
M100
K
K
I
D
A
T
R
M
S
R
F
I
E
M
N
Chicken
Gallus gallus
P12244
508
56874
L347
T
Q
F
C
H
H
F
L
E
G
K
I
K
P
H
Frog
Xenopus laevis
NP_001079815
505
56621
L347
K
E
F
C
D
S
F
L
E
G
K
V
K
P
H
Zebra Danio
Brachydanio rerio
NP_998529
509
56615
V345
I
S
F
C
T
S
F
V
E
G
T
L
K
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
L347
E
A
F
L
K
K
F
L
D
G
K
L
K
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17770
493
55134
L343
S
K
F
T
Q
N
Y
L
D
G
S
V
K
P
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
93
71.8
N.A.
64.4
20.2
N.A.
21.2
20.4
21.3
20.4
N.A.
22.1
N.A.
20.2
N.A.
Protein Similarity:
100
98.5
94.8
81.2
N.A.
80.9
32.4
N.A.
29.6
33.2
30.5
31.4
N.A.
34.2
N.A.
33.2
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
46.6
6.6
N.A.
13.3
6.6
6.6
13.3
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
73.3
20
N.A.
33.3
20
20
20
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
42
34
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
42
9
0
0
0
17
0
0
0
0
9
0
% D
% Glu:
9
9
0
9
0
0
0
0
34
0
0
0
9
25
0
% E
% Phe:
0
42
50
0
0
42
42
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
0
42
0
0
0
42
50
0
0
0
0
0
% G
% His:
0
0
0
0
17
17
0
0
0
0
0
0
0
0
59
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
0
25
0
0
0
% I
% Lys:
17
17
0
0
9
9
0
17
0
34
34
0
75
0
0
% K
% Leu:
0
0
0
9
0
0
42
42
0
9
34
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
0
% M
% Asn:
34
0
0
0
0
9
0
0
0
0
0
0
0
0
34
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
42
0
% P
% Gln:
0
17
0
0
9
0
0
0
0
0
0
9
0
9
0
% Q
% Arg:
0
0
0
0
0
0
9
0
0
9
9
0
9
0
0
% R
% Ser:
9
9
0
0
0
17
0
25
9
0
9
0
0
0
0
% S
% Thr:
17
0
0
9
9
9
0
0
0
0
9
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
9
0
0
0
17
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _