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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VWCE All Species: 4.24
Human Site: S782 Identified Species: 23.33
UniProt: Q96DN2 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DN2 NP_689931.2 955 99915 S782 E A P V N C S S C P G P P T A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001083081 1123 117180 S950 E A P V N C S S C T G T P I A
Dog Lupus familis XP_540922 905 94795 S733 A E A P V N C S S C P G T P A
Cat Felis silvestris
Mouse Mus musculus Q3U515 929 97658 E756 R N A R G D T E V P V N C S S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505246 480 50013 P308 A F S T S S F P R G P S A P S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 81.5 78.4 N.A. 76.8 N.A. N.A. 35.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 82.3 82.4 N.A. 81.8 N.A. N.A. 40.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 80 13.3 N.A. 6.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 80 13.3 N.A. 26.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 40 40 0 0 0 0 0 0 0 0 0 20 0 60 % A
% Cys: 0 0 0 0 0 40 20 0 40 20 0 0 20 0 0 % C
% Asp: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % D
% Glu: 40 20 0 0 0 0 0 20 0 0 0 0 0 0 0 % E
% Phe: 0 20 0 0 0 0 20 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 20 0 0 0 0 20 40 20 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 20 0 0 40 20 0 0 0 0 0 20 0 0 0 % N
% Pro: 0 0 40 20 0 0 0 20 0 40 40 20 40 40 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 20 0 0 20 0 0 0 0 20 0 0 0 0 0 0 % R
% Ser: 0 0 20 0 20 20 40 60 20 0 0 20 0 20 40 % S
% Thr: 0 0 0 20 0 0 20 0 0 20 0 20 20 20 0 % T
% Val: 0 0 0 40 20 0 0 0 20 0 20 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _