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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MBD6 All Species: 1.21
Human Site: S253 Identified Species: 4.44
UniProt: Q96DN6 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DN6 NP_443129.3 1003 101201 S253 P A P H A S S S P P S D P P L
Chimpanzee Pan troglodytes XP_509166 475 46684
Rhesus Macaque Macaca mulatta XP_001100706 770 77799 K96 S L L S A A A K A Q H P P L P
Dog Lupus familis XP_849726 1007 101225 S257 H T S S S P P S D P S L F H C
Cat Felis silvestris
Mouse Mus musculus Q8VHK1 1201 126791 N294 R A L K D F W N L H D P T A L
Rat Rattus norvegicus NP_001164037 1005 101384 P255 P H A S S S P P S D S P L F H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001076461 792 82865 L118 L Q P P A L T L T S P G G G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.8 75.6 95.2 N.A. 20.5 93.2 N.A. N.A. N.A. N.A. 24.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 47.1 75.9 96.1 N.A. 30.8 94.8 N.A. N.A. N.A. N.A. 35.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 13.3 20 N.A. 13.3 20 N.A. N.A. N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 26.6 26.6 N.A. 20 26.6 N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 29 15 0 43 15 15 0 15 0 0 0 0 15 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % C
% Asp: 0 0 0 0 15 0 0 0 15 15 15 15 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 15 0 0 0 0 0 0 15 15 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 15 15 15 0 % G
% His: 15 15 0 15 0 0 0 0 0 15 15 0 0 15 15 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 15 0 0 0 15 0 0 0 0 0 0 0 % K
% Leu: 15 15 29 0 0 15 0 15 15 0 0 15 15 15 29 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % N
% Pro: 29 0 29 15 0 15 29 15 15 29 15 43 29 15 15 % P
% Gln: 0 15 0 0 0 0 0 0 0 15 0 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 15 0 15 43 29 29 15 29 15 15 43 0 0 0 0 % S
% Thr: 0 15 0 0 0 0 15 0 15 0 0 0 15 0 15 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _