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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SGEF
All Species:
8.79
Human Site:
S419
Identified Species:
21.48
UniProt:
Q96DR7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DR7
NP_056410.3
871
97360
S419
K
P
L
R
S
T
W
S
Q
L
S
A
V
K
R
Chimpanzee
Pan troglodytes
XP_001146545
871
97327
S419
K
P
L
R
S
T
W
S
Q
L
S
A
V
K
R
Rhesus Macaque
Macaca mulatta
XP_001082733
709
80324
G273
L
P
E
V
V
E
L
G
I
L
D
Q
L
S
T
Dog
Lupus familis
XP_854672
589
67618
Q153
G
L
S
Q
T
V
S
Q
E
E
R
K
R
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3U5C8
713
80377
G277
L
P
E
V
L
E
S
G
V
L
D
T
L
S
T
Rat
Rattus norvegicus
Q5BKC9
701
80989
L265
L
Q
P
E
E
T
K
L
Q
E
A
M
F
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511351
1102
121173
S651
K
P
L
R
S
T
W
S
Q
L
S
V
V
K
R
Chicken
Gallus gallus
XP_426718
770
85723
Q334
G
L
S
E
T
I
S
Q
E
E
R
K
R
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116755
606
69197
E170
D
E
P
R
F
Y
Q
E
I
K
E
R
G
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_494706
1136
128641
C638
G
S
Q
R
S
L
W
C
E
L
P
E
V
R
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.1
37.3
65.5
N.A.
37
28.4
N.A.
52.8
67.7
N.A.
33.1
N.A.
N.A.
N.A.
27.1
N.A.
Protein Similarity:
100
98.5
52.9
66.2
N.A.
51.7
45.2
N.A.
62
74.4
N.A.
47.7
N.A.
N.A.
N.A.
44.8
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
13.3
13.3
N.A.
93.3
0
N.A.
6.6
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
100
20
26.6
N.A.
20
26.6
N.A.
93.3
20
N.A.
6.6
N.A.
N.A.
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
10
20
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% D
% Glu:
0
10
20
20
10
20
0
10
30
30
10
10
0
10
20
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
30
0
0
0
0
0
0
20
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
20
0
0
0
0
0
0
% I
% Lys:
30
0
0
0
0
0
10
0
0
10
0
20
0
30
0
% K
% Leu:
30
20
30
0
10
10
10
10
0
60
0
0
20
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
50
20
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
10
10
0
0
10
20
40
0
0
10
0
20
0
% Q
% Arg:
0
0
0
50
0
0
0
0
0
0
20
10
20
10
30
% R
% Ser:
0
10
20
0
40
0
30
30
0
0
30
0
0
20
0
% S
% Thr:
0
0
0
0
20
40
0
0
0
0
0
10
0
0
20
% T
% Val:
0
0
0
20
10
10
0
0
10
0
0
10
40
0
0
% V
% Trp:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _