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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATG4C
All Species:
27.27
Human Site:
T402
Identified Species:
42.86
UniProt:
Q96DT6
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DT6
NP_116241.2
458
52497
T402
K
R
A
S
E
E
I
T
K
M
L
K
F
S
S
Chimpanzee
Pan troglodytes
XP_001159697
366
41520
K311
T
D
Y
L
E
F
V
K
G
I
L
S
L
E
Y
Rhesus Macaque
Macaca mulatta
XP_001086218
458
52551
T402
E
R
A
S
E
E
I
T
K
M
L
K
F
S
S
Dog
Lupus familis
XP_852273
458
52523
T402
K
R
A
S
E
E
I
T
K
M
L
K
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q811C2
458
52068
T402
E
R
A
S
E
E
I
T
K
M
L
K
I
S
S
Rat
Rattus norvegicus
NP_001101418
458
52091
T402
E
R
A
S
E
E
I
T
K
M
L
K
I
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514370
459
52127
T402
E
R
A
S
E
E
I
T
K
V
L
K
A
S
S
Chicken
Gallus gallus
Q6PZ02
393
44512
K338
D
W
C
H
Q
I
K
K
L
S
L
V
R
G
A
Frog
Xenopus laevis
Q5XH30
450
51749
T393
E
K
A
A
E
E
L
T
K
V
L
K
S
S
T
Zebra Danio
Brachydanio rerio
Q6DG88
394
44435
R339
D
D
W
C
A
Q
I
R
K
V
S
N
C
R
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650452
668
74736
Q567
D
N
F
M
E
S
V
Q
L
Y
L
H
P
M
R
Honey Bee
Apis mellifera
XP_393739
477
54008
P415
T
N
F
M
E
I
A
P
S
Y
L
V
P
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786847
723
81931
P657
E
Q
L
C
K
E
L
P
T
V
V
S
P
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S929
467
51510
S402
P
L
E
S
L
D
P
S
L
A
L
G
F
Y
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S3X7
506
55337
D451
G
F
L
I
K
D
E
D
D
W
D
T
W
K
S
Conservation
Percent
Protein Identity:
100
79.9
98.2
94.5
N.A.
90.3
89.5
N.A.
83.2
28.1
68.1
26.8
N.A.
26.5
30.3
N.A.
28
Protein Similarity:
100
79.9
98.9
97.3
N.A.
95.6
95.4
N.A.
88
42.5
82.7
46
N.A.
42
46.3
N.A.
41.4
P-Site Identity:
100
13.3
93.3
93.3
N.A.
86.6
86.6
N.A.
80
6.6
53.3
13.3
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
26.6
100
93.3
N.A.
93.3
93.3
N.A.
93.3
20
93.3
26.6
N.A.
20
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
21.5
Protein Similarity:
N.A.
N.A.
N.A.
41.1
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
47
7
7
0
7
0
0
7
0
0
7
0
7
% A
% Cys:
0
0
7
14
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
20
14
0
0
0
14
0
7
7
0
7
0
0
0
7
% D
% Glu:
40
0
7
0
67
54
7
0
0
0
0
0
0
14
0
% E
% Phe:
0
7
14
0
0
7
0
0
0
0
0
0
20
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
7
0
0
7
0
7
14
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
0
14
47
0
0
7
0
0
20
0
0
% I
% Lys:
14
7
0
0
14
0
7
14
54
0
0
47
0
7
0
% K
% Leu:
0
7
14
7
7
0
14
0
20
0
80
0
7
7
0
% L
% Met:
0
0
0
14
0
0
0
0
0
34
0
0
0
7
0
% M
% Asn:
0
14
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
7
0
0
0
0
0
7
14
0
0
0
0
20
0
0
% P
% Gln:
0
7
0
0
7
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
40
0
0
0
0
0
7
0
0
0
0
7
7
7
% R
% Ser:
0
0
0
47
0
7
0
7
7
7
7
14
7
47
47
% S
% Thr:
14
0
0
0
0
0
0
47
7
0
0
7
0
0
7
% T
% Val:
0
0
0
0
0
0
14
0
0
27
7
14
0
0
0
% V
% Trp:
0
7
7
0
0
0
0
0
0
7
0
0
7
0
0
% W
% Tyr:
0
0
7
0
0
0
0
0
0
14
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _