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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPKC All Species: 12.42
Human Site: S322 Identified Species: 27.33
UniProt: Q96DU7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DU7 NP_079470.1 683 75207 S322 L Y S H L K C S P L C P V P R
Chimpanzee Pan troglodytes XP_524271 683 75280 S322 L Y S H L K C S P L C P V P R
Rhesus Macaque Macaca mulatta XP_001092036 566 61727 E225 S A D G S W K E L Y T D G S R
Dog Lupus familis XP_855312 621 68771 P277 I T P E T P E P E A Q P V G P
Cat Felis silvestris
Mouse Mus musculus Q7TS72 678 74474 S316 L C S H L E C S S L C P V P R
Rat Rattus norvegicus Q80ZG2 678 74445 S316 L C S H L E C S S L C P V P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415039 637 69972 A276 L G G P E E E A G A V P P S S
Frog Xenopus laevis NP_001088157 516 58252 K175 V P S L F I R K L S S S S G L
Zebra Danio Brachydanio rerio XP_691475 657 73298 D293 I P T V I I T D D G M E V S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572875 669 73198 L284 Y I Q Y S K S L L E V P M P R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795627 356 40840 V15 G S L N M M D V S N N S G G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 79.6 75.8 N.A. 75.5 75.5 N.A. N.A. 38.2 39.8 39.2 N.A. 33.5 N.A. N.A. 29.8
Protein Similarity: 100 99.4 80.2 79.6 N.A. 81.2 81.2 N.A. N.A. 52.2 51.2 52.4 N.A. 48.6 N.A. N.A. 39
P-Site Identity: 100 100 6.6 13.3 N.A. 80 80 N.A. N.A. 13.3 6.6 6.6 N.A. 26.6 N.A. N.A. 0
P-Site Similarity: 100 100 6.6 20 N.A. 86.6 86.6 N.A. N.A. 26.6 13.3 26.6 N.A. 40 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 0 10 0 19 0 0 0 0 0 % A
% Cys: 0 19 0 0 0 0 37 0 0 0 37 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 10 10 0 0 10 0 0 0 % D
% Glu: 0 0 0 10 10 28 19 10 10 10 0 10 0 0 0 % E
% Phe: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 10 0 0 0 0 10 10 0 0 19 28 10 % G
% His: 0 0 0 37 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 10 0 0 10 19 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 28 10 10 0 0 0 0 0 0 0 % K
% Leu: 46 0 10 10 37 0 0 10 28 37 0 0 0 0 19 % L
% Met: 0 0 0 0 10 10 0 0 0 0 10 0 10 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % N
% Pro: 0 19 10 10 0 10 0 10 19 0 0 64 10 46 10 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 55 % R
% Ser: 10 10 46 0 19 0 10 37 28 10 10 19 10 28 10 % S
% Thr: 0 10 10 0 10 0 10 0 0 0 10 0 0 0 0 % T
% Val: 10 0 0 10 0 0 0 10 0 0 19 0 55 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 19 0 10 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _