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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITPKC All Species: 11.82
Human Site: S384 Identified Species: 26
UniProt: Q96DU7 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96DU7 NP_079470.1 683 75207 S384 A S D P E D R S G S K P W K K
Chimpanzee Pan troglodytes XP_524271 683 75280 S384 A S D P E D R S G S K P W K K
Rhesus Macaque Macaca mulatta XP_001092036 566 61727 T287 P S T D G S Q T A P G T D C L
Dog Lupus familis XP_855312 621 68771 F339 T V L K Y S P F V V S F R K H
Cat Felis silvestris
Mouse Mus musculus Q7TS72 678 74474 A378 T S D P E D R A G S K P W K K
Rat Rattus norvegicus Q80ZG2 678 74445 S378 T S D P E D R S G S K P W K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415039 637 69972 S338 Q K P R V S K S W R K I K N M
Frog Xenopus laevis NP_001088157 516 58252 S237 H W S P F V V S F K K Q Y P W
Zebra Danio Brachydanio rerio XP_691475 657 73298 K355 A F L Q T Q Q K A H K S W K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572875 669 73198 Q346 R K I R N I V Q W T P F F Q T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795627 356 40840 K77 F V Q S F K K K Y P W V Q L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 79.6 75.8 N.A. 75.5 75.5 N.A. N.A. 38.2 39.8 39.2 N.A. 33.5 N.A. N.A. 29.8
Protein Similarity: 100 99.4 80.2 79.6 N.A. 81.2 81.2 N.A. N.A. 52.2 51.2 52.4 N.A. 48.6 N.A. N.A. 39
P-Site Identity: 100 100 6.6 6.6 N.A. 86.6 93.3 N.A. N.A. 13.3 20 33.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 100 20 6.6 N.A. 93.3 93.3 N.A. N.A. 20 26.6 40 N.A. 20 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 0 0 0 0 0 10 19 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 0 0 37 10 0 37 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 10 0 0 19 0 0 10 10 0 0 19 10 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 37 0 10 0 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % H
% Ile: 0 0 10 0 0 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 19 0 10 0 10 19 19 0 10 64 0 10 55 46 % K
% Leu: 0 0 19 0 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 10 0 10 46 0 0 10 0 0 19 10 37 0 10 0 % P
% Gln: 10 0 10 10 0 10 19 10 0 0 0 10 10 10 0 % Q
% Arg: 10 0 0 19 0 0 37 0 0 10 0 0 10 0 0 % R
% Ser: 0 46 10 10 0 28 0 46 0 37 10 10 0 0 0 % S
% Thr: 28 0 10 0 10 0 0 10 0 10 0 10 0 0 10 % T
% Val: 0 19 0 0 10 10 19 0 10 10 0 10 0 0 0 % V
% Trp: 0 10 0 0 0 0 0 0 19 0 10 0 46 0 10 % W
% Tyr: 0 0 0 0 10 0 0 0 10 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _