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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKC
All Species:
28.18
Human Site:
S609
Identified Species:
62
UniProt:
Q96DU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DU7
NP_079470.1
683
75207
S609
L
R
E
A
L
E
I
S
P
F
F
K
T
H
E
Chimpanzee
Pan troglodytes
XP_524271
683
75280
S609
L
R
E
A
L
E
I
S
P
F
F
K
T
H
E
Rhesus Macaque
Macaca mulatta
XP_001092036
566
61727
S495
G
S
R
W
G
W
G
S
P
D
A
G
V
V
G
Dog
Lupus familis
XP_855312
621
68771
S547
L
R
E
A
L
E
N
S
P
F
F
K
T
H
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
S604
L
R
E
T
L
E
N
S
P
F
F
K
T
H
E
Rat
Rattus norvegicus
Q80ZG2
678
74445
S604
L
R
D
T
L
E
N
S
P
F
F
K
T
H
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415039
637
69972
S559
I
R
A
T
L
E
T
S
P
F
F
K
C
H
E
Frog
Xenopus laevis
NP_001088157
516
58252
F445
A
L
E
K
S
E
F
F
Q
S
H
E
V
V
G
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
S580
I
R
D
T
L
E
M
S
P
F
F
K
T
H
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
S561
I
R
A
T
L
A
V
S
E
F
F
Q
T
H
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
E285
S
P
F
F
S
N
H
E
V
I
G
S
S
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79.6
75.8
N.A.
75.5
75.5
N.A.
N.A.
38.2
39.8
39.2
N.A.
33.5
N.A.
N.A.
29.8
Protein Similarity:
100
99.4
80.2
79.6
N.A.
81.2
81.2
N.A.
N.A.
52.2
51.2
52.4
N.A.
48.6
N.A.
N.A.
39
P-Site Identity:
100
100
13.3
93.3
N.A.
86.6
80
N.A.
N.A.
66.6
13.3
73.3
N.A.
53.3
N.A.
N.A.
0
P-Site Similarity:
100
100
13.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
73.3
20
93.3
N.A.
73.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
19
28
0
10
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
19
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
0
0
46
0
0
73
0
10
10
0
0
10
0
0
73
% E
% Phe:
0
0
10
10
0
0
10
10
0
73
73
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
10
0
0
0
10
10
0
0
19
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
73
0
% H
% Ile:
28
0
0
0
0
0
19
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
64
0
0
0
% K
% Leu:
46
10
0
0
73
0
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
28
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
73
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
73
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
19
0
0
82
0
10
0
10
10
0
0
% S
% Thr:
0
0
0
46
0
0
10
0
0
0
0
0
64
0
0
% T
% Val:
0
0
0
0
0
0
10
0
10
0
0
0
19
19
0
% V
% Trp:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _