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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKC
All Species:
5.76
Human Site:
T282
Identified Species:
12.67
UniProt:
Q96DU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DU7
NP_079470.1
683
75207
T282
G
S
W
T
Q
P
S
T
D
G
S
Q
T
A
P
Chimpanzee
Pan troglodytes
XP_524271
683
75280
T282
G
S
W
T
Q
P
S
T
D
G
S
Q
T
A
P
Rhesus Macaque
Macaca mulatta
XP_001092036
566
61727
A192
P
E
R
V
K
S
W
A
D
N
L
W
T
H
Q
Dog
Lupus familis
XP_855312
621
68771
P244
Q
D
G
P
L
E
E
P
E
P
G
E
L
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
D280
A
L
T
Q
P
G
T
D
G
L
R
D
D
S
V
Rat
Rattus norvegicus
Q80ZG2
678
74445
P282
Q
P
G
T
D
D
G
P
W
V
D
S
V
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415039
637
69972
V243
L
S
L
Q
R
G
E
V
V
M
A
T
S
G
L
Frog
Xenopus laevis
NP_001088157
516
58252
T142
T
S
P
P
L
P
E
T
T
S
V
L
D
I
P
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
D253
R
T
L
S
E
A
N
D
C
S
A
S
W
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
G249
Q
Q
H
S
L
P
L
G
S
P
T
S
P
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79.6
75.8
N.A.
75.5
75.5
N.A.
N.A.
38.2
39.8
39.2
N.A.
33.5
N.A.
N.A.
29.8
Protein Similarity:
100
99.4
80.2
79.6
N.A.
81.2
81.2
N.A.
N.A.
52.2
51.2
52.4
N.A.
48.6
N.A.
N.A.
39
P-Site Identity:
100
100
13.3
0
N.A.
0
6.6
N.A.
N.A.
6.6
26.6
0
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
20
13.3
N.A.
13.3
6.6
N.A.
N.A.
26.6
26.6
33.3
N.A.
26.6
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
10
0
0
19
0
0
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
10
0
19
28
0
10
10
19
0
0
% D
% Glu:
0
10
0
0
10
10
28
0
10
0
0
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
19
0
0
19
10
10
10
19
10
0
0
19
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
19
0
28
0
10
0
0
10
10
10
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% N
% Pro:
10
10
10
19
10
37
0
19
0
19
0
0
10
0
28
% P
% Gln:
28
10
0
19
19
0
0
0
0
0
0
19
0
0
10
% Q
% Arg:
10
0
10
0
10
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
37
0
19
0
10
19
0
10
19
19
28
10
10
10
% S
% Thr:
10
10
10
28
0
0
10
28
10
0
10
10
28
10
10
% T
% Val:
0
0
0
10
0
0
0
10
10
10
10
0
10
0
10
% V
% Trp:
0
0
19
0
0
0
10
0
10
0
0
10
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _