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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKC
All Species:
27.27
Human Site:
T549
Identified Species:
60
UniProt:
Q96DU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DU7
NP_079470.1
683
75207
T549
E
T
M
S
S
T
S
T
L
G
F
R
I
E
G
Chimpanzee
Pan troglodytes
XP_524271
683
75280
T549
E
T
M
S
S
T
S
T
L
G
F
R
I
E
G
Rhesus Macaque
Macaca mulatta
XP_001092036
566
61727
E437
L
K
R
F
C
Q
C
E
Q
R
S
L
E
Q
L
Dog
Lupus familis
XP_855312
621
68771
G489
V
S
S
T
S
T
L
G
F
R
I
E
G
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
T544
E
T
L
S
S
T
S
T
L
G
F
R
I
E
G
Rat
Rattus norvegicus
Q80ZG2
678
74445
T544
E
T
L
S
S
T
S
T
L
G
F
R
I
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415039
637
69972
T499
E
T
I
S
S
T
A
T
L
G
F
R
I
E
G
Frog
Xenopus laevis
NP_001088157
516
58252
I387
T
A
T
M
G
F
R
I
E
G
I
K
R
A
D
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
T520
E
T
I
S
S
T
A
T
L
G
F
R
I
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
T501
E
T
I
S
S
T
A
T
L
G
F
R
I
E
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
K227
G
F
R
I
E
G
V
K
K
G
D
G
H
S
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79.6
75.8
N.A.
75.5
75.5
N.A.
N.A.
38.2
39.8
39.2
N.A.
33.5
N.A.
N.A.
29.8
Protein Similarity:
100
99.4
80.2
79.6
N.A.
81.2
81.2
N.A.
N.A.
52.2
51.2
52.4
N.A.
48.6
N.A.
N.A.
39
P-Site Identity:
100
100
0
13.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
6.6
86.6
N.A.
86.6
N.A.
N.A.
6.6
P-Site Similarity:
100
100
6.6
26.6
N.A.
100
100
N.A.
N.A.
100
13.3
100
N.A.
100
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
28
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% D
% Glu:
64
0
0
0
10
0
0
10
10
0
0
10
10
64
0
% E
% Phe:
0
10
0
10
0
10
0
0
10
0
64
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
0
10
0
82
0
10
10
0
64
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
28
10
0
0
0
10
0
0
19
0
64
10
0
% I
% Lys:
0
10
0
0
0
0
0
10
10
0
0
10
0
0
10
% K
% Leu:
10
0
19
0
0
0
10
0
64
0
0
10
0
0
10
% L
% Met:
0
0
19
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
19
0
0
0
10
0
0
19
0
64
10
0
0
% R
% Ser:
0
10
10
64
73
0
37
0
0
0
10
0
0
10
10
% S
% Thr:
10
64
10
10
0
73
0
64
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _