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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKC
All Species:
6.06
Human Site:
Y316
Identified Species:
13.33
UniProt:
Q96DU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DU7
NP_079470.1
683
75207
Y316
G
E
L
L
T
H
L
Y
S
H
L
K
C
S
P
Chimpanzee
Pan troglodytes
XP_524271
683
75280
Y316
G
E
L
V
T
H
L
Y
S
H
L
K
C
S
P
Rhesus Macaque
Macaca mulatta
XP_001092036
566
61727
A219
C
P
S
K
E
P
S
A
D
G
S
W
K
E
L
Dog
Lupus familis
XP_855312
621
68771
T271
P
V
P
R
L
I
I
T
P
E
T
P
E
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
C310
G
E
L
V
T
N
L
C
S
H
L
E
C
S
S
Rat
Rattus norvegicus
Q80ZG2
678
74445
C310
R
D
L
V
T
N
L
C
S
H
L
E
C
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415039
637
69972
G270
A
V
I
I
T
D
L
G
G
P
E
E
E
A
G
Frog
Xenopus laevis
NP_001088157
516
58252
P169
G
C
G
G
S
P
V
P
S
L
F
I
R
K
L
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
P287
S
P
E
L
G
S
I
P
T
V
I
I
T
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
I278
Q
S
L
C
P
G
Y
I
Q
Y
S
K
S
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
S9
K
D
N
T
N
N
G
S
L
N
M
M
D
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79.6
75.8
N.A.
75.5
75.5
N.A.
N.A.
38.2
39.8
39.2
N.A.
33.5
N.A.
N.A.
29.8
Protein Similarity:
100
99.4
80.2
79.6
N.A.
81.2
81.2
N.A.
N.A.
52.2
51.2
52.4
N.A.
48.6
N.A.
N.A.
39
P-Site Identity:
100
93.3
0
0
N.A.
66.6
53.3
N.A.
N.A.
13.3
13.3
6.6
N.A.
13.3
N.A.
N.A.
0
P-Site Similarity:
100
100
0
6.6
N.A.
86.6
80
N.A.
N.A.
40
26.6
26.6
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% A
% Cys:
10
10
0
10
0
0
0
19
0
0
0
0
37
0
0
% C
% Asp:
0
19
0
0
0
10
0
0
10
0
0
0
10
10
10
% D
% Glu:
0
28
10
0
10
0
0
0
0
10
10
28
19
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
37
0
10
10
10
10
10
10
10
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
19
0
0
0
37
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
10
19
10
0
0
10
19
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
0
0
0
28
10
10
0
% K
% Leu:
0
0
46
19
10
0
46
0
10
10
37
0
0
10
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% M
% Asn:
0
0
10
0
10
28
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
19
10
0
10
19
0
19
10
10
0
10
0
10
19
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
10
10
10
0
10
10
10
10
46
0
19
0
10
37
28
% S
% Thr:
0
0
0
10
46
0
0
10
10
0
10
0
10
0
0
% T
% Val:
0
19
0
28
0
0
10
0
0
10
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
19
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _