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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITPKC
All Species:
12.73
Human Site:
Y457
Identified Species:
28
UniProt:
Q96DU7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96DU7
NP_079470.1
683
75207
Y457
R
P
F
V
P
A
Y
Y
G
M
V
L
Q
D
G
Chimpanzee
Pan troglodytes
XP_524271
683
75280
Y457
R
P
F
V
P
A
Y
Y
G
M
V
L
Q
D
G
Rhesus Macaque
Macaca mulatta
XP_001092036
566
61727
R349
Q
S
V
G
P
P
S
R
V
E
G
G
S
G
G
Dog
Lupus familis
XP_855312
621
68771
D401
Y
Y
G
M
V
Q
R
D
G
Q
A
F
N
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q7TS72
678
74474
Y452
R
P
F
V
P
A
Y
Y
G
M
V
Q
R
D
G
Rat
Rattus norvegicus
Q80ZG2
678
74445
Y452
R
P
F
V
P
T
Y
Y
G
M
V
Q
R
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415039
637
69972
H407
K
P
Y
V
P
A
Y
H
G
D
V
M
K
D
G
Frog
Xenopus laevis
NP_001088157
516
58252
N299
M
V
E
K
E
G
E
N
Y
N
Q
M
E
D
L
Zebra Danio
Brachydanio rerio
XP_691475
657
73298
H428
K
P
Y
V
P
A
Y
H
G
D
V
E
K
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572875
669
73198
G409
P
Y
V
P
V
Y
K
G
Q
V
T
S
E
D
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795627
356
40840
M139
N
S
E
K
Y
V
Q
M
Q
D
L
L
G
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79.6
75.8
N.A.
75.5
75.5
N.A.
N.A.
38.2
39.8
39.2
N.A.
33.5
N.A.
N.A.
29.8
Protein Similarity:
100
99.4
80.2
79.6
N.A.
81.2
81.2
N.A.
N.A.
52.2
51.2
52.4
N.A.
48.6
N.A.
N.A.
39
P-Site Identity:
100
100
13.3
6.6
N.A.
86.6
80
N.A.
N.A.
60
6.6
60
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
100
20
13.3
N.A.
93.3
86.6
N.A.
N.A.
93.3
20
86.6
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
46
0
0
0
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
28
0
0
0
73
0
% D
% Glu:
0
0
19
0
10
0
10
0
0
10
0
10
19
10
0
% E
% Phe:
0
0
37
0
0
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
0
0
10
10
0
10
0
10
64
0
10
10
10
10
73
% G
% His:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
0
0
19
0
0
10
0
0
0
0
0
19
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
28
0
0
10
% L
% Met:
10
0
0
10
0
0
0
10
0
37
0
19
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
10
0
10
0
0
10
0
0
% N
% Pro:
10
55
0
10
64
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
10
10
0
19
10
10
19
19
10
0
% Q
% Arg:
37
0
0
0
0
0
10
10
0
0
0
0
19
0
0
% R
% Ser:
0
19
0
0
0
0
10
0
0
0
0
10
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% T
% Val:
0
10
19
55
19
10
0
0
10
10
55
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
19
19
0
10
10
55
37
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _