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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRRF All Species: 4.55
Human Site: S134 Identified Species: 10
UniProt: Q96E11 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96E11 NP_620132.1 262 29277 S134 K L A L N Q I S Q I S M K S P
Chimpanzee Pan troglodytes XP_001135996 262 29306 S134 K L A L N Q I S Q I S M K S P
Rhesus Macaque Macaca mulatta XP_001089220 292 32097 L139 L V E D I I N L E E V N E E M
Dog Lupus familis XP_537859 262 29135 G134 K L A L N Q I G Q I S M K S P
Cat Felis silvestris
Mouse Mus musculus Q9D6S7 262 29032 G134 K V A L N Q I G Q I S M K S P
Rat Rattus norvegicus Q5RKI9 262 29133 G134 K L A L N Q I G Q I S M K S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512325 241 26791 Q114 F S L N Q L A Q I S M K S P Q
Chicken Gallus gallus XP_415395 259 28549 G131 K F P L N Q L G Q I S Q K S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002174 257 28422 G129 K F P L N Q L G Q I S M K S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648302 254 28466 A126 E H E L Q E L A Q I S R K N P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792740 188 20763 M61 P L N Q L G Q M T S K S S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 77.7 87.7 N.A. 85.1 85.1 N.A. 70.9 61.8 N.A. 57.6 N.A. 32.8 N.A. N.A. 36.6
Protein Similarity: 100 98.8 79.7 93.8 N.A. 92.7 91.2 N.A. 83.5 76.7 N.A. 74.4 N.A. 56.1 N.A. N.A. 52.6
P-Site Identity: 100 100 0 93.3 N.A. 86.6 93.3 N.A. 0 66.6 N.A. 73.3 N.A. 40 N.A. N.A. 13.3
P-Site Similarity: 100 100 20 93.3 N.A. 93.3 93.3 N.A. 0 73.3 N.A. 80 N.A. 73.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 46 0 0 0 10 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 19 0 0 10 0 0 10 10 0 0 10 10 0 % E
% Phe: 10 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 46 0 0 0 0 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 10 46 0 10 73 0 0 0 0 0 % I
% Lys: 64 0 0 0 0 0 0 0 0 0 10 10 73 0 0 % K
% Leu: 10 46 10 73 10 10 28 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 10 55 0 0 10 % M
% Asn: 0 0 10 10 64 0 10 0 0 0 0 10 0 10 0 % N
% Pro: 10 0 19 0 0 0 0 0 0 0 0 0 0 10 73 % P
% Gln: 0 0 0 10 19 64 10 10 73 0 0 10 0 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 10 0 0 0 0 0 19 0 19 73 10 19 73 10 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % T
% Val: 0 19 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _