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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRRF All Species: 13.33
Human Site: S207 Identified Species: 29.33
UniProt: Q96E11 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96E11 NP_620132.1 262 29277 S207 N T N K A K D S L R K V R T N
Chimpanzee Pan troglodytes XP_001135996 262 29306 S207 N T N K A K D S L R K V R T N
Rhesus Macaque Macaca mulatta XP_001089220 292 32097 A212 F P E C T A A A I K A I R E S
Dog Lupus familis XP_537859 262 29135 S207 N T N K A K D S L R K V R T N
Cat Felis silvestris
Mouse Mus musculus Q9D6S7 262 29032 N207 N T N K A K E N L R K V R T N
Rat Rattus norvegicus Q5RKI9 262 29133 N207 N T N K A K E N L R K V R T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512325 241 26791 L187 T N K A K E S L R K V R T N A
Chicken Gallus gallus XP_415395 259 28549 A204 S T N K S K E A L R K V R S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002174 257 28422 S202 F S N K S K D S L R R V R S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648302 254 28466 A199 L F V K Y R D A I R G V Q N E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792740 188 20763 R134 D K A K V N I R G A R S K Y I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 77.7 87.7 N.A. 85.1 85.1 N.A. 70.9 61.8 N.A. 57.6 N.A. 32.8 N.A. N.A. 36.6
Protein Similarity: 100 98.8 79.7 93.8 N.A. 92.7 91.2 N.A. 83.5 76.7 N.A. 74.4 N.A. 56.1 N.A. N.A. 52.6
P-Site Identity: 100 100 6.6 100 N.A. 86.6 86.6 N.A. 0 60 N.A. 66.6 N.A. 26.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 40 100 N.A. 100 100 N.A. 13.3 93.3 N.A. 93.3 N.A. 53.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 46 10 10 28 0 10 10 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 46 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 0 10 28 0 0 0 0 0 0 10 10 % E
% Phe: 19 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 0 19 0 0 10 0 0 10 % I
% Lys: 0 10 10 82 10 64 0 0 0 19 55 0 10 0 10 % K
% Leu: 10 0 0 0 0 0 0 10 64 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 46 10 64 0 0 10 0 19 0 0 0 0 0 19 55 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 10 0 10 10 73 19 10 73 0 0 % R
% Ser: 10 10 0 0 19 0 10 37 0 0 0 10 0 19 10 % S
% Thr: 10 55 0 0 10 0 0 0 0 0 0 0 10 46 0 % T
% Val: 0 0 10 0 10 0 0 0 0 0 10 73 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _