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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRRF
All Species:
20.61
Human Site:
S222
Identified Species:
45.33
UniProt:
Q96E11
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96E11
NP_620132.1
262
29277
S222
S
M
N
K
L
K
K
S
K
D
T
V
S
E
D
Chimpanzee
Pan troglodytes
XP_001135996
262
29306
S222
S
M
N
K
L
K
K
S
K
Y
T
V
S
E
D
Rhesus Macaque
Macaca mulatta
XP_001089220
292
32097
V227
G
M
N
L
N
P
E
V
E
G
M
L
I
R
V
Dog
Lupus familis
XP_537859
262
29135
S222
A
M
N
K
L
K
K
S
K
D
K
V
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6S7
262
29032
S222
A
M
N
K
L
K
K
S
K
D
K
T
S
E
D
Rat
Rattus norvegicus
Q5RKI9
262
29133
S222
A
M
N
K
L
K
K
S
K
D
K
T
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512325
241
26791
K202
M
N
K
L
K
K
S
K
D
K
V
A
E
D
T
Chicken
Gallus gallus
XP_415395
259
28549
F219
S
V
N
Q
V
K
K
F
K
S
K
V
S
E
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002174
257
28422
S217
A
I
S
Q
V
K
K
S
K
D
A
V
S
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648302
254
28466
Q214
H
I
R
K
L
K
K
Q
P
E
L
G
K
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792740
188
20763
E149
S
L
V
R
K
H
K
E
G
T
S
K
D
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
77.7
87.7
N.A.
85.1
85.1
N.A.
70.9
61.8
N.A.
57.6
N.A.
32.8
N.A.
N.A.
36.6
Protein Similarity:
100
98.8
79.7
93.8
N.A.
92.7
91.2
N.A.
83.5
76.7
N.A.
74.4
N.A.
56.1
N.A.
N.A.
52.6
P-Site Identity:
100
93.3
13.3
86.6
N.A.
80
80
N.A.
6.6
60
N.A.
53.3
N.A.
33.3
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
33.3
93.3
N.A.
86.6
86.6
N.A.
13.3
80
N.A.
93.3
N.A.
53.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
46
0
0
10
28
73
% D
% Glu:
0
0
0
0
0
0
10
10
10
10
0
0
10
55
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
10
10
0
10
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
19
0
0
0
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
10
55
19
82
82
10
64
10
37
10
10
0
0
% K
% Leu:
0
10
0
19
55
0
0
0
0
0
10
10
0
0
0
% L
% Met:
10
55
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
64
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
19
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
37
0
10
0
0
0
10
55
0
10
10
0
64
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
19
19
0
10
10
% T
% Val:
0
10
10
0
19
0
0
10
0
0
10
46
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _