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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MRRF All Species: 9.7
Human Site: Y47 Identified Species: 21.33
UniProt: Q96E11 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96E11 NP_620132.1 262 29277 Y47 G H R Q Y M A Y S A V P V R H
Chimpanzee Pan troglodytes XP_001135996 262 29306 Y47 G H R Q Y M A Y S A V P V R H
Rhesus Macaque Macaca mulatta XP_001089220 292 32097 V54 C F Q G S S S V M A L G L K C
Dog Lupus familis XP_537859 262 29135 F47 D H E Q S M A F P A L P V R H
Cat Felis silvestris
Mouse Mus musculus Q9D6S7 262 29032 Y47 G H R Q Y S A Y P A V P V R H
Rat Rattus norvegicus Q5RKI9 262 29133 H47 D H I Q Y S A H P A V P V R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512325 241 26791 T36 I Q T R H F A T K K A K A K G
Chicken Gallus gallus XP_415395 259 28549 C44 L L D G C R H C A H P L L L A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002174 257 28422 A43 Q V S Q C P V A L P N Y A R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648302 254 28466 V41 E N T K Y L Q V A R D Y A K G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792740 188 20763
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 77.7 87.7 N.A. 85.1 85.1 N.A. 70.9 61.8 N.A. 57.6 N.A. 32.8 N.A. N.A. 36.6
Protein Similarity: 100 98.8 79.7 93.8 N.A. 92.7 91.2 N.A. 83.5 76.7 N.A. 74.4 N.A. 56.1 N.A. N.A. 52.6
P-Site Identity: 100 100 6.6 60 N.A. 86.6 60 N.A. 6.6 0 N.A. 20 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 40 73.3 N.A. 86.6 66.6 N.A. 26.6 13.3 N.A. 20 N.A. 40 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 55 10 19 55 10 0 28 0 10 % A
% Cys: 10 0 0 0 19 0 0 10 0 0 0 0 0 0 10 % C
% Asp: 19 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % D
% Glu: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 10 0 10 0 0 0 0 0 0 0 % F
% Gly: 28 0 0 19 0 0 0 0 0 0 0 10 0 0 19 % G
% His: 0 46 0 0 10 0 10 10 0 10 0 0 0 0 46 % H
% Ile: 10 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 10 0 10 0 28 0 % K
% Leu: 10 10 0 0 0 10 0 0 10 0 19 10 19 10 0 % L
% Met: 0 0 0 0 0 28 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 28 10 10 46 0 0 0 % P
% Gln: 10 10 10 55 0 0 10 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 28 10 0 10 0 0 0 10 0 0 0 55 0 % R
% Ser: 0 0 10 0 19 28 10 0 19 0 0 0 0 0 0 % S
% Thr: 0 0 19 0 0 0 0 10 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 10 19 0 0 37 0 46 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 46 0 0 28 0 0 0 19 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _