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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUS1 All Species: 18.18
Human Site: S279 Identified Species: 57.14
UniProt: Q96E22 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96E22 NP_612468.1 293 33224 S279 I S Y E D F F S A L R Q Y A A
Chimpanzee Pan troglodytes XP_518713 293 33156 S279 I S Y E D F F S A L R Q Y A A
Rhesus Macaque Macaca mulatta XP_001110733 293 33212 S279 I S Y E D F F S A L R Q Y A A
Dog Lupus familis XP_541219 293 33196 S279 I S Y E D F F S A L R Q Y A A
Cat Felis silvestris
Mouse Mus musculus Q99LJ8 297 33467 S283 I S Y E D F F S A L R Q Y A A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517963 172 19446 L160 Y E D F L S A L H C Y A A C E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6DHR8 274 31258 D260 A S Y D D L Y D A L Q R F A G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12063 375 42539 R361 V I Y S V F I R G L R Q Y A G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.9 92.4 N.A. 89.2 N.A. N.A. 47.4 N.A. N.A. 56.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 98.9 94.1 N.A. 91.9 N.A. N.A. 53.5 N.A. N.A. 70.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 N.A. N.A. 40 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 0 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 13 0 75 0 0 13 13 88 63 % A
% Cys: 0 0 0 0 0 0 0 0 0 13 0 0 0 13 0 % C
% Asp: 0 0 13 13 75 0 0 13 0 0 0 0 0 0 0 % D
% Glu: 0 13 0 63 0 0 0 0 0 0 0 0 0 0 13 % E
% Phe: 0 0 0 13 0 75 63 0 0 0 0 0 13 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 25 % G
% His: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % H
% Ile: 63 13 0 0 0 0 13 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 13 13 0 13 0 88 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 13 75 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 13 0 0 75 13 0 0 0 % R
% Ser: 0 75 0 13 0 13 0 63 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 0 88 0 0 0 13 0 0 0 13 0 75 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _