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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC99
All Species:
28.48
Human Site:
S145
Identified Species:
52.22
UniProt:
Q96EA4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EA4
NP_060255.3
605
70120
S145
K
E
L
L
S
C
K
S
E
E
L
R
V
M
S
Chimpanzee
Pan troglodytes
XP_001148181
602
69364
S145
K
E
L
L
S
C
K
S
E
E
L
R
V
M
S
Rhesus Macaque
Macaca mulatta
XP_001091769
601
69887
S145
K
E
L
L
S
C
K
S
E
E
L
R
V
M
S
Dog
Lupus familis
XP_536434
603
69824
S145
K
E
L
L
S
C
K
S
E
E
M
R
I
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q923A2
608
70218
E145
E
L
L
A
H
K
S
E
E
L
R
L
L
S
E
Rat
Rattus norvegicus
Q3KR99
597
69094
E145
E
L
L
S
H
K
S
E
E
L
R
L
L
S
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508244
599
69687
S145
K
E
C
L
A
A
K
S
E
E
L
H
V
M
S
Chicken
Gallus gallus
XP_414505
608
71149
T145
K
E
I
I
A
A
K
T
E
E
L
H
M
M
S
Frog
Xenopus laevis
Q6NRW2
610
70759
S146
T
E
V
L
A
N
K
S
E
E
L
R
M
M
S
Zebra Danio
Brachydanio rerio
A7MD70
590
68945
T147
A
E
A
L
N
S
K
T
E
E
L
R
A
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10567
882
101931
F195
A
E
K
A
A
E
R
F
E
A
Q
A
N
E
L
Sea Urchin
Strong. purpuratus
XP_794989
564
64872
L146
V
K
D
M
G
H
E
L
E
Q
L
R
F
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LME2
871
99988
L216
K
D
A
V
I
T
K
L
E
A
S
A
A
E
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
91.4
87.5
N.A.
73.8
73.2
N.A.
66.1
59.5
54.4
46.1
N.A.
N.A.
N.A.
21
25.9
Protein Similarity:
100
96.8
94.7
93.5
N.A.
82.5
82.8
N.A.
80
75.6
71.9
64.6
N.A.
N.A.
N.A.
42.1
47.4
P-Site Identity:
100
100
100
86.6
N.A.
13.3
13.3
N.A.
73.3
53.3
66.6
46.6
N.A.
N.A.
N.A.
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
80
86.6
86.6
73.3
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
16
16
31
16
0
0
0
16
0
16
16
0
0
% A
% Cys:
0
0
8
0
0
31
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
70
0
0
0
8
8
16
100
62
0
0
0
16
16
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
16
8
0
0
0
0
0
16
0
0
0
% H
% Ile:
0
0
8
8
8
0
0
0
0
0
0
0
8
0
0
% I
% Lys:
54
8
8
0
0
16
70
0
0
0
0
0
0
0
0
% K
% Leu:
0
16
47
54
0
0
0
16
0
16
62
16
16
8
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
8
0
16
54
0
% M
% Asn:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
16
54
0
0
8
% R
% Ser:
0
0
0
8
31
8
16
47
0
0
8
0
0
16
54
% S
% Thr:
8
0
0
0
0
8
0
16
0
0
0
0
0
8
8
% T
% Val:
8
0
8
8
0
0
0
0
0
0
0
0
31
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _