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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK2
All Species:
18.18
Human Site:
S124
Identified Species:
44.44
UniProt:
Q96ED9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ED9
NP_001093646.1
719
83164
S124
L
V
L
G
C
A
I
S
C
E
K
K
Q
D
H
Chimpanzee
Pan troglodytes
XP_524125
500
57793
D45
A
Y
V
L
N
Q
I
D
P
S
W
F
N
E
A
Rhesus Macaque
Macaca mulatta
XP_001099564
718
83173
N128
L
I
L
G
C
A
V
N
C
E
Q
K
Q
E
Y
Dog
Lupus familis
XP_542044
717
82945
S124
L
V
L
G
C
A
I
S
C
E
K
K
Q
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMK6
716
83365
S124
L
V
L
G
C
A
I
S
C
E
K
K
Q
E
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514454
774
89971
S179
L
V
L
G
C
A
I
S
C
E
K
K
Q
E
H
Chicken
Gallus gallus
Q5ZJ27
718
82961
N126
L
I
L
G
C
A
V
N
C
E
R
K
Q
E
H
Frog
Xenopus laevis
Q6NRB0
721
84488
S125
L
V
L
G
C
A
I
S
C
D
K
K
E
E
H
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
K124
L
I
L
G
C
A
V
K
C
D
R
K
Q
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
N125
L
V
L
G
C
A
V
N
C
A
E
K
Q
S
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.2
49.2
92.3
N.A.
85.6
N.A.
N.A.
68.7
45.7
59
47
N.A.
32.4
N.A.
N.A.
N.A.
Protein Similarity:
100
69.4
71.3
96.2
N.A.
92.4
N.A.
N.A.
79.7
65.9
78.7
68.4
N.A.
54.2
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
60
93.3
N.A.
86.6
N.A.
N.A.
93.3
66.6
80
53.3
N.A.
60
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
100
100
100
93.3
N.A.
86.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
90
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
90
0
0
0
90
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
20
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
60
10
0
10
80
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
50
% H
% Ile:
0
30
0
0
0
0
60
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
50
90
0
0
0
% K
% Leu:
90
0
90
10
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
30
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
80
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
0
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
60
10
0
0
0
40
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
40
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _