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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEH1L
All Species:
10.61
Human Site:
S335
Identified Species:
21.21
UniProt:
Q96EE3
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EE3
NP_001013455.1
360
39649
S335
G
S
S
Q
Q
G
T
S
N
P
S
L
G
S
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860726
360
39739
S335
G
N
S
Q
Q
G
N
S
N
P
S
L
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R2U0
360
39756
S335
G
S
S
Q
L
G
N
S
N
P
S
L
S
S
N
Rat
Rattus norvegicus
Q5XFW8
322
35529
V298
E
S
V
D
G
Q
W
V
C
I
S
D
V
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516945
324
35581
N300
S
S
Q
L
G
N
S
N
A
S
L
G
S
N
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4FZW5
360
39707
G335
N
S
Y
Q
G
F
F
G
S
S
V
G
S
A
G
Zebra Danio
Brachydanio rerio
Q6TGU2
364
39798
A335
G
S
S
G
P
S
A
A
L
S
A
V
G
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610343
354
39496
T330
E
P
A
P
P
T
P
T
L
A
T
T
A
S
A
Honey Bee
Apis mellifera
XP_396810
408
45120
P335
E
T
S
I
A
A
T
P
P
N
H
S
T
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781224
444
49387
H335
P
S
M
T
G
G
M
H
S
R
Q
D
Y
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53011
349
39104
D325
I
L
S
S
A
G
D
D
G
K
V
R
L
W
K
Red Bread Mold
Neurospora crassa
Q7RZF5
304
33367
S280
G
N
V
L
A
A
S
S
D
N
N
K
V
T
L
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98
N.A.
96.1
29.7
N.A.
86.3
N.A.
90.8
81.8
N.A.
53
58.5
N.A.
57.4
Protein Similarity:
100
N.A.
N.A.
99.1
N.A.
98
48.3
N.A.
87.7
N.A.
95.5
89
N.A.
70.5
72.3
N.A.
66.6
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
73.3
13.3
N.A.
6.6
N.A.
13.3
26.6
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
73.3
20
N.A.
26.6
N.A.
26.6
46.6
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.5
26.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
43.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
25
17
9
9
9
9
9
0
9
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
9
9
9
0
0
17
0
0
0
% D
% Glu:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
9
34
42
0
9
9
0
0
17
25
9
9
% G
% His:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
17
% K
% Leu:
0
9
0
17
9
0
0
0
17
0
9
25
9
0
9
% L
% Met:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
9
17
0
0
0
9
17
9
25
17
9
0
0
17
17
% N
% Pro:
9
9
0
9
17
0
9
9
9
25
0
0
0
17
9
% P
% Gln:
0
0
9
34
17
9
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% R
% Ser:
9
59
50
9
0
9
17
34
17
25
34
9
25
25
9
% S
% Thr:
0
9
0
9
0
9
17
9
0
0
9
9
9
9
17
% T
% Val:
0
0
17
0
0
0
0
9
0
0
17
9
17
9
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _