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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTMR8
All Species:
4.55
Human Site:
S516
Identified Species:
9.09
UniProt:
Q96EF0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96EF0
NP_060147.2
704
78919
S516
P
K
Q
S
M
L
E
S
L
L
E
I
K
K
Q
Chimpanzee
Pan troglodytes
XP_521093
710
79404
S516
P
K
Q
S
M
L
E
S
L
L
E
I
K
K
Q
Rhesus Macaque
Macaca mulatta
XP_001097351
710
79638
N516
A
K
Q
S
I
L
E
N
L
L
E
I
K
K
Q
Dog
Lupus familis
XP_534530
779
88802
N576
F
P
Q
A
F
E
F
N
E
A
F
L
L
Q
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE11
617
70914
N436
I
H
S
C
Q
F
G
N
F
L
G
N
C
Q
K
Rat
Rattus norvegicus
Q6AXQ4
602
69333
R421
F
G
H
K
F
S
S
R
I
G
H
G
D
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F452
629
71949
E448
G
T
C
H
K
E
R
E
D
L
K
I
F
E
K
Frog
Xenopus laevis
Q52KU6
602
69712
I421
G
H
K
F
S
S
R
I
G
H
G
D
K
N
H
Zebra Danio
Brachydanio rerio
Q6TEL0
632
72485
R451
Q
K
E
R
L
D
M
R
L
H
E
K
T
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611791
689
78732
E506
E
S
G
I
H
P
R
E
P
L
G
D
V
L
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22712
1006
113596
E757
E
E
I
R
R
K
D
E
K
I
E
E
L
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P47147
688
80133
N497
E
D
E
T
N
L
I
N
L
S
R
I
S
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96
46
N.A.
51.5
33.3
N.A.
N.A.
59.7
34.2
52.1
N.A.
44.5
N.A.
23.5
N.A.
Protein Similarity:
100
98.8
97.6
61.8
N.A.
68
49.5
N.A.
N.A.
73
50.5
69.3
N.A.
60.3
N.A.
39
N.A.
P-Site Identity:
100
100
80
6.6
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
20
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
33.3
N.A.
26.6
13.3
N.A.
N.A.
33.3
13.3
33.3
N.A.
6.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
47.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
9
9
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
9
0
0
0
9
9
0
9
0
0
17
9
0
0
% D
% Glu:
25
9
17
0
0
17
25
25
9
0
42
9
0
9
0
% E
% Phe:
17
0
0
9
17
9
9
0
9
0
9
0
9
9
0
% F
% Gly:
17
9
9
0
0
0
9
0
9
9
25
9
0
0
0
% G
% His:
0
17
9
9
9
0
0
0
0
17
9
0
0
0
9
% H
% Ile:
9
0
9
9
9
0
9
9
9
9
0
42
0
0
9
% I
% Lys:
0
34
9
9
9
9
0
0
9
0
9
9
34
42
25
% K
% Leu:
0
0
0
0
9
34
0
0
42
50
0
9
17
9
9
% L
% Met:
0
0
0
0
17
0
9
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
34
0
0
0
9
0
9
9
% N
% Pro:
17
9
0
0
0
9
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
0
34
0
9
0
0
0
0
0
0
0
0
17
25
% Q
% Arg:
0
0
0
17
9
0
25
17
0
0
9
0
0
9
9
% R
% Ser:
0
9
9
25
9
17
9
17
0
9
0
0
9
0
9
% S
% Thr:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _